دواعي استعمال ريلفار اليبتا 100/25مكجم انهايلر 30 جرعة

Fluticasone furoate 100 mcg + vilanterol 25 mcg inhalation powder (Ellipta inhaler), 30 metered doses, marketed in Egypt.

• Maintenance treatment of chronic obstructive pulmonary disease (COPD) - 100/25 mcg strength onlyDailyMed (U.S. National Library of Medicine)
• Maintenance treatment of asthma (US label: patients aged 5 years and older, strength-dependent)DailyMed (U.S. National Library of Medicine)

• COPD, most common (>=3%): nasopharyngitis, upper respiratory tract infection, headache, oral candidiasis, back pain, pneumonia, bronchitis, sinusitis, cough, oropharyngeal pain, arthralgia, hypertension.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Primary treatment of status asthmaticus or other acute episodes of COPD or asthma requiring intensive measures.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Severe hypersensitivity to milk proteins or hypersensitivity to fluticasone furoate, vilanterol or any excipient.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• LABA monotherapy increases the risk of serious asthma-related events; do not initiate in acutely deteriorating disease or use for acute symptoms; do not combine with another LABA.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Oropharyngeal candidiasis, increased pneumonia risk in COPD, immunosuppression, adrenal suppression when switching from systemic corticosteroids, paradoxical bronchospasm, reduced bone mineral density, glaucoma/cataracts and growth effects may occur.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Strong CYP3A4 inhibitors (e.g. ketoconazole)Increase exposure to both components; use with caution (systemic corticosteroid and cardiovascular effects).DailyMed (U.S. National Library of Medicine)
• MAO inhibitors and tricyclic antidepressantsMay potentiate cardiovascular effects of vilanterol; use with extreme caution.DailyMed (U.S. National Library of Medicine)
• Beta-blockersMay block bronchodilator effect and produce severe bronchospasm.DailyMed (U.S. National Library of Medicine)
• Non-potassium-sparing diureticsECG changes and/or hypokalaemia may be worsened.DailyMed (U.S. National Library of Medicine)

• Insufficient human data on use in pregnancy; rat studies with inhaled fluticasone furoate and vilanterol showed no fetal structural abnormalities; poorly controlled asthma itself carries perinatal risks.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)