دواعي استعمال ريميكابيوتك 500مجم/2مل امبول

Amikacin 500 mg/2 ml solution for injection, single vial, marketed in Egypt.

• Short-term treatment of serious infections due to susceptible Gram-negative bacteria (e.g. Pseudomonas, E. coli, Proteus, Klebsiella-Enterobacter-Serratia, Acinetobacter), including septicaemia, respiratory, bone/joint, CNS, skin, intra-abdominal, burn and complicated urinary tract infectionsDailyMed (U.S. National Library of Medicine)

• Auditory, vestibular and renal toxicity and neuromuscular blockade, more frequent with renal impairment, other ototoxic/nephrotoxic drugs, longer treatment or higher doses.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• History of hypersensitivity to amikacin; hypersensitivity or serious toxic reactions to other aminoglycosides may contraindicate use.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Boxed warning: potential ototoxicity (vestibular and permanent bilateral auditory), nephrotoxicity and neuromuscular blockade/respiratory paralysis; close clinical observation required; safety beyond 14 days not established.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Aminoglycosides can cause fetal harm; contains sodium metabisulfite, which may cause allergic-type reactions in susceptible people.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Measure peak and trough serum concentrations (avoid peaks >35 mcg/mL and troughs >10 mcg/mL); reassess renal function periodically.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Semi-synthetic aminoglycoside derived from kanamycin A; binds the bacterial 30S ribosomal subunit and disrupts protein synthesis (per directory pharmacology note).