دواعي استعمال ريمينيل 16مجم 7 كبسول

Galantamine 16 mg prolonged-release capsules, pack of 7, Janssen-Cilag > Soficopharm, marketed in Egypt.

• Mild to moderate dementia of the Alzheimer typeDailyMed (U.S. National Library of Medicine)

• Most common (>=5%): nausea, vomiting, diarrhoea, dizziness, headache and decreased appetite.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Known hypersensitivity to galantamine hydrobromide or to any excipient.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Serious skin reactions (Stevens-Johnson syndrome, acute generalised exanthematous pustulosis): stop at the first appearance of rash unless clearly not drug-related.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Vagotonic effects: bradycardia and all types of heart block, with dose-related increase in syncope; all patients are considered at risk for cardiac conduction effects.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Possible increase in gastric acid secretion: monitor for gastrointestinal bleeding, especially with ulcer history or NSAID use; may cause bladder outflow obstruction and seizures; use with care in severe asthma or obstructive pulmonary disease.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Likely to exaggerate succinylcholine-type neuromuscular blockade during anaesthesia.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Higher mortality was seen with galantamine than placebo in two 2-year trials in mild cognitive impairment (not an approved use).نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Anticholinergic medicationsGalantamine may interfere with the activity of anticholinergic medications.DailyMed (U.S. National Library of Medicine)
• Succinylcholine, other cholinesterase inhibitors, cholinergic agonists (e.g. bethanechol)A synergistic effect is expected when given concurrently.DailyMed (U.S. National Library of Medicine)

• No adequate human data; in animals galantamine caused developmental toxicity (morphological abnormalities, decreased growth) at doses similar to or above clinical doses.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• No data on presence in human milk or effects on the breastfed infant; weigh benefits of breastfeeding against the mother's need for the drug.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Monitor for seizures, respiratory adverse effects in patients with asthma/COPD, and signs of gastrointestinal bleeding.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Competitive, reversible acetylcholinesterase inhibitor that is thought to enhance cholinergic function (US label).