دواعي استعمال ريناجيل 800مجم 180 قرص

Sevelamer 800 mg film-coated tablets, pack of 180, Genzyme/Sanofi.

• Control of serum phosphorus in chronic kidney disease patients on dialysisDailyMed (U.S. National Library of Medicine)

• In a 52-week study, reactions >5%: vomiting (22%), nausea (20%), diarrhoea (19%), dyspepsia (16%), abdominal pain (9%), flatulence (8%) and constipation (8%).نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)

• Bowel obstruction; known hypersensitivity to sevelamer hydrochloride or excipients.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)

• Dysphagia, oesophageal tablet retention, bowel obstruction, perforation, GI bleeding, colitis and ulceration have been reported; caution in severe GI motility disorders or major GI surgery.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)
• May reduce vitamins D, E, K (clotting factors) and folic acid; monitor bicarbonate and chloride.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)

• Oral drugs with narrow therapeutic index (e.g. ciclosporin, tacrolimus, levothyroxine)Sevelamer may reduce their bioavailability; consider separating administration times and monitor levels.DailyMed (U.S. National Library of Medicine)

• Not absorbed systemically, so fetal exposure is not expected; may lower fat-soluble vitamins and folic acid in pregnancy - consider supplementation.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)
• Not absorbed systemically; breastfeeding is not expected to expose the infant.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)

• Monitor serum phosphorus, bicarbonate and chloride; consider fat-soluble vitamin and folate status.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)