دواعي استعمال رينتنسار 150مجم 20 اقراص

Irbesartan 150 mg scored tablets, pack of 20; angiotensin II receptor blocker for hypertension.

• Treatment of hypertension, to lower blood pressure.الفئة: AdultsDailyMed (U.S. National Library of Medicine)
• Treatment of diabetic nephropathy with elevated serum creatinine and proteinuria (>300 mg/day) in patients with type 2 diabetes and hypertension.الفئة: AdultsDailyMed (U.S. National Library of Medicine)

• Hypertension trials: diarrhoea, dyspepsia/heartburn and fatigue (>=1% and more than placebo). Diabetic nephropathy: hyperkalaemia, dizziness, orthostatic dizziness and orthostatic hypotension.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Hypersensitivity to any component.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Coadministration with aliskiren in patients with diabetes.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• BOXED WARNING - Fetal toxicity: discontinue as soon as possible when pregnancy is detected; drugs acting on the renin-angiotensin system can cause injury and death to the developing fetus.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Symptomatic hypotension may occur in volume- or salt-depleted patients; correct before starting.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Changes in renal function, including acute renal failure, may occur in susceptible patients (e.g. renal artery stenosis, severe heart failure).نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Potassium-sparing diuretics, potassium supplements, salt substitutesMay increase serum potassium.DailyMed (U.S. National Library of Medicine)
• LithiumIncreased serum lithium and toxicity; monitor lithium levels.DailyMed (U.S. National Library of Medicine)
• NSAIDs including COX-2 inhibitorsMay worsen renal function and attenuate antihypertensive effect.DailyMed (U.S. National Library of Medicine)
• ACE inhibitors, other ARBs, aliskiren (dual RAS blockade)Increased risk of hypotension, hyperkalaemia and renal impairment; avoid aliskiren in diabetes.DailyMed (U.S. National Library of Medicine)

• Use in the second and third trimesters reduces fetal renal function and increases fetal and neonatal morbidity and death; discontinue when pregnancy is detected.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Breastfeeding is not recommended during treatment.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Selectively blocks the angiotensin II AT1 receptor, inhibiting vasoconstriction and aldosterone release.