دواعي استعمال رييباندين 1مجم 10 اقراص

رييباندين 1مجم 10 اقراص: أقراص ريباجلينيد 1 مجم للفم، محفز لإفراز الإنسولين من مجموعة الميجليتينيد.

• Adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus (not for type 1 diabetes or diabetic ketoacidosis).الفئة: Adults with type 2 diabetes mellitusDailyMed (U.S. National Library of Medicine)

• Hypoglycemia is the most common adverse reaction; others include upper respiratory infection, headache, sinusitis, arthralgia, nausea, diarrhea and back pain.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Concomitant use of gemfibrozil.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Known hypersensitivity to repaglinide or any inactive ingredient.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Hypoglycemia, which can be severe; risk increased by skipped meals, exercise, renal/hepatic impairment and interacting drugs; beta-blockers may mask symptoms.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Not indicated in combination with NPH insulin (myocardial ischemia events in trials).نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• No conclusive evidence of macrovascular risk reduction.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• GemfibrozilContraindicated: markedly increases repaglinide exposure.DailyMed (U.S. National Library of Medicine)
• ClopidogrelAvoid; if unavoidable start 0.5 mg before each meal and do not exceed 4 mg/day.DailyMed (U.S. National Library of Medicine)
• CyclosporineDo not exceed 6 mg repaglinide per day.DailyMed (U.S. National Library of Medicine)
• Strong CYP3A4/CYP2C8 inhibitors or inducersDose adjustment may be needed because exposure changes.DailyMed (U.S. National Library of Medicine)

• Limited human data have not identified a drug-associated risk of major birth defects, miscarriage or adverse outcomes; poorly controlled diabetes in pregnancy carries maternal and fetal risks.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• No human milk data; because of potential hypoglycemia in breastfed infants, use while breastfeeding is not recommended.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Monitor blood glucose and HbA1c to assess response; assess response at least one week after each dose change.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Short-acting stimulation of insulin release from pancreatic beta cells.