دواعي استعمال Requib-prolib 8 mg

Ropinirole 8 mg prolonged-release tablets (non-ergoline dopamine agonist), pack of 28.

• Treatment of Parkinson's disease.الفئة: AdultsDailyMed (U.S. National Library of Medicine)

• Adverse reactions discussed in labeling include somnolence, syncope, orthostatic hypotension, hallucinations, dyskinesia and impulse-control behaviors.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• History of hypersensitivity/allergic reaction (urticaria, angioedema, rash, pruritus) to ropinirole or any excipient.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Falling asleep during activities of daily living (including driving) and somnolence.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Syncope, hypotension and orthostatic hypotension, especially during dose escalation.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Hallucinations/psychotic-like behavior, dyskinesia, impulse-control/compulsive behaviors, withdrawal-emergent hyperpyrexia and confusion, and fibrotic complications are listed warnings.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• CYP1A2 inhibitors or inducers (e.g., ciprofloxacin; smoking)CYP1A2 is the major metabolic enzyme; starting or stopping a potent inhibitor/inducer may require dose adjustment. Ciprofloxacin increases ropinirole exposure; smoking is expected to increase clearance.DailyMed (U.S. National Library of Medicine)

• No adequate data on developmental risk in pregnant women; adverse developmental effects (neurobehavioral impairment, teratogenicity at high doses) in rats.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• No data on presence in human milk; inhibition of lactation is expected because ropinirole inhibits prolactin secretion.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Monitor at least weekly during titration and for signs of orthostatic hypotension, especially during dose escalation.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Thought to act by stimulating dopamine D2 receptors within the caudate-putamen (US label 12.1).