دواعي استعمال ريسكيوركس 0.4مجم/مل 10 امبول

Naloxone 0.4 mg/ml solution for IM/IV/SC injection, 10 ampoules; opioid receptor antagonist used for opioid poisoning.

• Complete or partial reversal of opioid depression, including respiratory depression, induced by natural and synthetic opioids.DailyMed (U.S. National Library of Medicine)
• Diagnosis of suspected or known acute opioid overdosage.DailyMed (U.S. National Library of Medicine)
• علاج حالات التسمم بالمواد الأفيونية

• Postoperative use: hypotension, hypertension, ventricular tachycardia/fibrillation, dyspnea, pulmonary edema and cardiac arrest; abrupt reversal may cause nausea, vomiting, sweating, tachycardia, tremulousness and seizures.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Known hypersensitivity to naloxone hydrochloride or any other ingredient.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Use cautiously in persons (including neonates of mothers) physically dependent on opioids: abrupt reversal may precipitate acute withdrawal.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Keep patients under continued surveillance and repeat doses as needed, since some opioids act longer than naloxone.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Not effective against respiratory depression due to non-opioid drugs.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• BuprenorphineLarge naloxone doses are needed to antagonize buprenorphine; reversal is gradual and shorter.DailyMed (U.S. National Library of Medicine)

• No adequate well-controlled studies in pregnant women; animal studies showed no teratogenicity; use only if clearly needed; in opioid-dependent pregnant women, consider risk of precipitating fetal withdrawal.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Not known whether excreted in human milk; use caution in nursing women.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Competitive antagonist at mu, kappa and delta opioid receptors.