دواعي استعمال ريسبنزو 600مجم 10 اقراص
معلومات من نشرات دوائية ومراجع موثقة، مع مصدر كل معلومة. السعر الحالي: 206ج.م.
عن الدواء
Linezolid 600 mg film-coated tablets, pack of 10; oxazolidinone antibacterial.
دواعي الاستعمال
- Nosocomial pneumoniaDailyMed (U.S. National Library of Medicine)
- Community-acquired pneumoniaDailyMed (U.S. National Library of Medicine)
- Complicated skin and skin structure infections, including diabetic foot infections without osteomyelitisDailyMed (U.S. National Library of Medicine)
- Uncomplicated skin and skin structure infectionsDailyMed (U.S. National Library of Medicine)
- Vancomycin-resistant Enterococcus faecium infectionsDailyMed (U.S. National Library of Medicine)
موانع الاستعمال
- Known hypersensitivity to linezolid or other product components.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
- Patients taking any MAO-A or MAO-B inhibitor or within two weeks of taking one.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
تحذيرات واحتياطات
- Myelosuppression (anaemia, leukopenia, pancytopenia, thrombocytopenia); monitor complete blood counts weekly.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
- Peripheral and optic neuropathy, mainly with treatment beyond the maximum recommended 28 days.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
- Mortality imbalance seen in an investigational study of catheter-related bloodstream infections; not indicated for Gram-negative infections.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
- Other labelled warnings: serotonin syndrome, C. difficile-associated diarrhoea, lactic acidosis, convulsions, rhabdomyolysis, hypoglycaemia.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
التداخلات الدوائية
- Monoamine oxidase inhibitorsLinezolid is a reversible nonselective MAO inhibitor; concomitant MAOI use contraindicated.DailyMed (U.S. National Library of Medicine)
- Adrenergic and serotonergic agentsPotential for interaction (pressor response, serotonin syndrome).DailyMed (U.S. National Library of Medicine)
الحمل والرضاعة
- Published and postmarketing case reports have not identified a drug-associated risk of major birth defects, miscarriage or adverse maternal/fetal outcomes; embryo-fetal lethality seen in mice at 6.5 times human exposure.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
- Linezolid is present in breast milk (about 6-9% of the infant therapeutic dose); no information on effects on the breastfed infant.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
المتابعة أثناء العلاج
- Weekly complete blood counts, particularly with treatment longer than two weeks or pre-existing myelosuppression.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
المصادر
- السعر: قوائم أسعار الأدوية المنشورة في مصر.
- DailyMed (U.S. National Library of Medicine)
- WHO Collaborating Centre for Drug Statistics Methodology