دواعي استعمال ريتاباكت 1% مرهم موضعي 10جم

Retapamulin 1% topical ointment, 10 g tube (Debeiky > Lamar Pharma); pleuromutilin antibacterial for impetigo and small infected skin lesions.

• Topical treatment of impetigo (up to 100 cm2 in adults or 2% body surface area in children) due to methicillin-susceptible Staphylococcus aureus or Streptococcus pyogenes.الفئة: Adults and children aged 9 months and olderDailyMed (U.S. National Library of Medicine)

• Drug-related adverse events occurred in 5.5% of patients; the most common was application-site irritation (1.4%).نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• None stated in the US label.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Discontinue and wipe off the ointment in case of sensitization or severe local irritation, and use alternative therapy.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Not for systemic or mucosal use: not for ingestion or oral, intranasal, ophthalmic or intravaginal use.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Ketoconazole (oral) and other CYP3A4 inhibitorsOral ketoconazole increased retapamulin AUC and Cmax by 81% after topical use on abraded skin; dose adjustment unnecessary because systemic exposure is low.DailyMed (U.S. National Library of Medicine)

• No adequate and well-controlled studies in pregnant women; animal studies showed no malformations; use in pregnancy only if potential benefit outweighs potential risk.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Not known whether retapamulin is excreted in human milk; use caution in nursing women.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)