دواعي استعمال ريفاكسيروز 550مجم 10 اقراص

Rifaximin 550 mg film-coated tablets, pack of 10, by Averroes Pharma (Egypt).

• Reduction in risk of overt hepatic encephalopathy recurrenceالفئة: AdultsDailyMed (U.S. National Library of Medicine)
• Irritable bowel syndrome with diarrhea (IBS-D)الفئة: AdultsDailyMed (U.S. National Library of Medicine)
• Travelers' diarrhea caused by noninvasive E. coli (200 mg strength regimen)الفئة: 12 years and olderDailyMed (U.S. National Library of Medicine)

• HE: peripheral edema, nausea, dizziness, fatigue, ascites, muscle spasms, pruritus, anemia. IBS-D: ALT increased, nausea. TD: headache.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)

• Hypersensitivity to rifaximin, any rifamycin antimicrobial or any component (exfoliative dermatitis, angioedema, anaphylaxis reported).نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)

• Not effective for diarrhea with fever/blood in stool or due to pathogens other than E. coli; stop if symptoms worsen or persist beyond 24-48 hours.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)
• Clostridioides difficile-associated diarrhea may occur.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)
• Caution with P-glycoprotein inhibitors (e.g. cyclosporine), which greatly increase systemic exposure.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)
• Severe cutaneous adverse reactions (SJS/TEN) reported in patients with cirrhosis; discontinue at first signs.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)

• Cyclosporine and other P-gp inhibitorsCyclosporine increased rifaximin Cmax 83-fold and AUC 124-fold; use caution.DailyMed (U.S. National Library of Medicine)
• WarfarinINR changes reported; monitor INR and adjust warfarin as needed.DailyMed (U.S. National Library of Medicine)

• No human data; teratogenic in rats and rabbits; may cause fetal harm - advise pregnant women of potential risk.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)
• No information on presence in human milk; weigh benefits of breastfeeding against maternal need.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)

• Monitor INR and prothrombin time when co-administered with warfarin.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)

• ريفاكسيمين: Binds the beta-subunit of bacterial DNA-dependent RNA polymerase, blocking transcription.