دواعي استعمال ريكادوسين 8 مجم أقراص

Silodosin 8 mg scored film-coated tablets (selective alpha-1A adrenoceptor antagonist) for benign prostatic hyperplasia symptoms, pack of 14, by Medizen Pharmaceutical Industries, Egypt.

• Treatment of the signs and symptoms of benign prostatic hyperplasia (not indicated for hypertension)الفئة: Adult menDailyMed (U.S. National Library of Medicine)

• Most common (>2%): retrograde ejaculation, dizziness, diarrhoea, orthostatic hypotension, headache, nasopharyngitis and nasal congestion.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)

• Severe renal impairment (CrCl <30 ml/min); severe hepatic impairment (Child-Pugh >=10); concomitant strong CYP3A4 inhibitors (e.g. ketoconazole, clarithromycin, itraconazole, ritonavir); hypersensitivity to silodosin or ingredients.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)

• Postural hypotension and possible syncope when starting; caution with driving or hazardous tasks.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)
• Rule out prostate carcinoma before starting, as symptoms overlap with BPH.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)
• Intraoperative floppy iris syndrome during cataract surgery; patients should inform their ophthalmologist.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)
• Do not combine with other alpha-blockers; caution with antihypertensives.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)

• Strong CYP3A4 inhibitors (ketoconazole, itraconazole, clarithromycin, ritonavir)Ketoconazole raised silodosin Cmax 3.8-fold and AUC 3.2-fold; contraindicated.DailyMed (U.S. National Library of Medicine)
• Strong P-glycoprotein inhibitors (e.g. cyclosporine)May increase silodosin concentrations; not recommended.DailyMed (U.S. National Library of Medicine)
• Other alpha-blockersPharmacodynamic interaction expected; do not combine.DailyMed (U.S. National Library of Medicine)
• PDE5 inhibitors (sildenafil, tadalafil)More positive orthostatic test results; use with caution.DailyMed (U.S. National Library of Medicine)
• AntihypertensivesSlightly higher incidence of dizziness and orthostatic hypotension; use with caution.DailyMed (U.S. National Library of Medicine)

• Silodosin is not indicated for use in females.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)
• Silodosin is not indicated for use in females.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)

• Selective antagonist of postsynaptic alpha-1A adrenoreceptors in prostate, bladder base/neck and prostatic urethra; relaxation improves urine flow and BPH symptoms (US silodosin labels).