دواعي استعمال ريمانتافلو 100مجم 10 كبسول

Rimantaflu 100 mg capsules (rimantadine hydrochloride 100 mg, pack of 10) by Jedco, an Egyptian oral adamantane antiviral (influenza A uncoating inhibitor).

• Prophylaxis and treatment of illness caused by influenza A virus in adults (17 years and older).DailyMed (U.S. National Library of Medicine)
• Prophylaxis against influenza A virus in children 1 to 16 years of age.DailyMed (U.S. National Library of Medicine)

• Most frequent (1-3%): insomnia, dizziness, headache, nervousness, fatigue, nausea, vomiting, anorexia, dry mouth, abdominal pain, asthenia.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)

• Known hypersensitivity to adamantane-class drugs, including rimantadine and amantadine.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)

• Seizure-like activity may occur in patients with a history of epilepsy; discontinue if seizures develop.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)
• Influenza A resistance to rimantadine emerges and is transmissible; cross-resistance with amantadine; consult CDC guidance on circulating strain resistance.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)

• Live attenuated intranasal influenza vaccineNot evaluated together; because of potential interference, do not give the live vaccine until 48 hours after stopping rimantadine, and do not give rimantadine until two weeks after the live vaccine.DailyMed (U.S. National Library of Medicine)
• Acetaminophen / aspirinReduced rimantadine peak concentration and AUC by about 10-11%.DailyMed (U.S. National Library of Medicine)

• No adequate and well-controlled studies in pregnant women; embryotoxic in rats at high doses and crosses the placenta in mice.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)
• Should not be given to nursing mothers because of adverse effects in offspring of treated rats; concentrated in rat milk.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)

• Not fully understood; appears to act early in viral replication, possibly inhibiting uncoating of influenza A virus; the M2 protein determines susceptibility.