دواعي استعمال Ringer lactate (compound sodium lactate) (Mottahedoon) i.v. infusion 500 ml (rubber cap)

Compound sodium lactate (Ringer's lactate) solution for intravenous infusion, 500 ml, used as a fluid and electrolyte replenisher.

• مصدر للماء والإلكتروليتات أو كعامل قلويالفئة: Adults and pediatric patientsDailyMed (US National Library of Medicine)

• Infusion site reactions (phlebitis, extravasation, inflammation, swelling, rash, pruritus, erythema, pain, burning).نشرة دولية لتركيبة مكافئة · DailyMed (US National Library of Medicine)
• Hypersensitivity/infusion reactions (angioedema, chest discomfort, tachy- or bradycardia, hypotension, bronchospasm, dyspnea, urticaria, rash, fever, headache).نشرة دولية لتركيبة مكافئة · DailyMed (US National Library of Medicine)
• Hyperkalemia, hyponatremia, hypervolemia and hyponatremic encephalopathy.نشرة دولية لتركيبة مكافئة · DailyMed (US National Library of Medicine)

• حديثو الولادة (28 يومًا أو أقل) الذين يتلقون السيفترياكسون حتى عبر خطوط منفصلة.نشرة دولية لتركيبة مكافئة · DailyMed (US National Library of Medicine)
• فرط الحساسية المعروف لأي من المكونات.نشرة دولية لتركيبة مكافئة · DailyMed (US National Library of Medicine)

• Air embolism risk with pressurized infusion or series connection of flexible containers.نشرة دولية لتركيبة مكافئة · DailyMed (US National Library of Medicine)
• Hypersensitivity reactions including anaphylaxis and angioedema; stop infusion immediately if they occur.نشرة دولية لتركيبة مكافئة · DailyMed (US National Library of Medicine)
• Hyperkalemia risk in predisposed patients (severe renal impairment, dehydration, burns, heart failure, hyperkalemia-associated drugs); potassium content is insufficient to treat severe hypokalemia.نشرة دولية لتركيبة مكافئة · DailyMed (US National Library of Medicine)
• May cause hyponatremia and hyponatremic encephalopathy; higher risk in children, elderly, patients on diuretics or with SIADH; avoid rapid correction.نشرة دولية لتركيبة مكافئة · DailyMed (US National Library of Medicine)
• Contains calcium; avoid in hypercalcemia, calcium renal calculi, or with thiazides or vitamin D.نشرة دولية لتركيبة مكافئة · DailyMed (US National Library of Medicine)
• Fluid overload including pulmonary edema depending on volume and rate.نشرة دولية لتركيبة مكافئة · DailyMed (US National Library of Medicine)
• Lactate is metabolized to bicarbonate and may cause or worsen metabolic alkalosis; may interfere with interpretation of serum lactate in severe metabolic acidosis.نشرة دولية لتركيبة مكافئة · DailyMed (US National Library of Medicine)

• CeftriaxoneCalcium-ceftriaxone precipitation; contraindicated together in neonates; in older patients give sequentially with thorough line flushing.DailyMed (US National Library of Medicine)
• Hyperkalemia-associated drugs (potassium-sparing diuretics, ACE inhibitors, ARBs, calcineurin inhibitors)Increased risk of severe hyperkalemia; avoid or monitor serum potassium.DailyMed (US National Library of Medicine)
• Drugs associated with hyponatremia (diuretics, SIADH-inducing drugs)Increased risk of hyponatremia; avoid or monitor serum sodium.DailyMed (US National Library of Medicine)
• Thiazide diuretics, vitamin DIncreased risk of hypercalcemia.DailyMed (US National Library of Medicine)
• Corticosteroids, corticotropinRisk of hypernatremia and volume overload.DailyMed (US National Library of Medicine)
• LithiumIncreased renal lithium clearance may lower lithium levels; monitor lithium.DailyMed (US National Library of Medicine)
• DigoxinCalcium may increase digoxin effects and toxicity; consider reducing volume/rate.DailyMed (US National Library of Medicine)
• Drugs with pH-dependent renal eliminationAlkalinization decreases clearance of alkaline drugs and increases clearance of acidic drugs.DailyMed (US National Library of Medicine)

• Used for decades during labor and delivery; exposure in pregnancy is not expected to cause major birth defects, miscarriage or adverse maternal or fetal outcomes; no animal reproduction studies.نشرة دولية لتركيبة مكافئة · DailyMed (US National Library of Medicine)
• Not expected to harm a breastfed infant; no data on presence in human milk.نشرة دولية لتركيبة مكافئة · DailyMed (US National Library of Medicine)

• Monitor fluid balance, serum electrolytes (potassium, sodium, calcium) and acid-base status, especially in prolonged use, children, elderly and renal/hepatic impairment.نشرة دولية لتركيبة مكافئة · DailyMed (US National Library of Medicine)