دواعي استعمال رينجر لاكتات (مركب صوديوم لاكتات) اوتوسوكا محلول وريدي 500 مل

Compound sodium lactate (lactated Ringer's) solution for intravenous infusion by Otsuka, 500 ml, listed in Egyptian price directories.

• Restoration of extracellular fluid and electrolyte balance or replacement of extracellular fluid loss where isotonic electrolyte concentrations are sufficientالفئة: Adults, elderly and childrenUK electronic Medicines Compendium (emc)
• Short-term volume replacement (alone or with a colloid) in hypovolaemia or hypotensionالفئة: Adults, elderly and childrenUK electronic Medicines Compendium (emc)
• Treatment of mild to moderate metabolic acidosis (except lactic acidosis)الفئة: Adults, elderly and childrenUK electronic Medicines Compendium (emc)

• Hypersensitivity/infusion reactions including anaphylactic or anaphylactoid reactions, angioedema, urticaria, bronchospasm.نشرة دولية لتركيبة مكافئة · UK electronic Medicines Compendium (emc)
• Hyperkalaemia, hospital-acquired hyponatraemia and acute hyponatraemic encephalopathy (post-marketing).نشرة دولية لتركيبة مكافئة · UK electronic Medicines Compendium (emc)
• Infusion-site reactions such as phlebitis, inflammation, swelling, pain or burning.نشرة دولية لتركيبة مكافئة · UK electronic Medicines Compendium (emc)

• Concomitant ceftriaxone in newborns (28 days of age or younger), even via separate lines, because of fatal ceftriaxone-calcium precipitation.نشرة دولية لتركيبة مكافئة · UK electronic Medicines Compendium (emc)
• Extracellular hyperhydration or hypervolaemia; severe renal insufficiency with oliguria/anuria; uncompensated cardiac failure.نشرة دولية لتركيبة مكافئة · UK electronic Medicines Compendium (emc)
• Hyperkalaemia, hypercalcaemia, metabolic alkalosis, severe metabolic acidosis, ascitic cirrhosis.نشرة دولية لتركيبة مكافئة · UK electronic Medicines Compendium (emc)
• Hyperlactataemia/lactic acidosis or impaired lactate utilisation (e.g. severe hepatic insufficiency); known hypersensitivity to sodium lactate; concomitant digitalis therapy.نشرة دولية لتركيبة مكافئة · UK electronic Medicines Compendium (emc)

• Risk of hospital-acquired hyponatraemia and acute hyponatraemic encephalopathy, particularly with non-osmotic vasopressin release (e.g. SIADH, post-operative stress) or vasopressin-agonist drugs; monitor serum sodium.نشرة دولية لتركيبة مكافئة · UK electronic Medicines Compendium (emc)
• Fluid and/or solute overload with pulmonary congestion and oedema may occur depending on volume and rate; use with caution in renal impairment, cardiac or pulmonary failure and conditions causing sodium retention.نشرة دولية لتركيبة مكافئة · UK electronic Medicines Compendium (emc)
• Lactate is metabolised to bicarbonate and may cause or worsen metabolic alkalosis; monitor glucose in type 2 diabetes because lactate is a gluconeogenic substrate.نشرة دولية لتركيبة مكافئة · UK electronic Medicines Compendium (emc)
• Must not be given through the same line as citrate-anticoagulated blood (calcium content); in patients over 28 days ceftriaxone must not be given simultaneously through the same line.نشرة دولية لتركيبة مكافئة · UK electronic Medicines Compendium (emc)

• CeftriaxoneContraindicated in neonates; in older patients must not be given simultaneously via the same line because of calcium-ceftriaxone precipitation.UK electronic Medicines Compendium (emc)
• Digitalis glycosidesCalcium may increase digitalis effects and lead to serious arrhythmia.UK electronic Medicines Compendium (emc)
• Potassium-sparing diuretics, ACE inhibitors, angiotensin II antagonists, tacrolimus, ciclosporinIncreased risk of hyperkalaemia due to potassium content.UK electronic Medicines Compendium (emc)
• Drugs increasing vasopressin effect (e.g. carbamazepine, SSRIs, desmopressin, oxytocin)Increased risk of hospital-acquired hyponatraemia.UK electronic Medicines Compendium (emc)

• Can be used during pregnancy and lactation provided electrolyte and fluid balance are controlled; use special caution during labour with oxytocin because of serum-sodium risk.نشرة دولية لتركيبة مكافئة · UK electronic Medicines Compendium (emc)
• Can be used during lactation when fluid and electrolyte balance is controlled; calcium is distributed into breast milk.نشرة دولية لتركيبة مكافئة · UK electronic Medicines Compendium (emc)

• Monitor fluid balance, serum electrolytes (especially sodium and potassium) and acid-base balance before and during administration.نشرة دولية لتركيبة مكافئة · UK electronic Medicines Compendium (emc)