سعر ريسالدين بلس 12+2 اقراص Risedronate sodium 35 مجم 2022

Combination pack (12+2 film-coated tablets) of calcium carbonate and risedronate sodium 35 mg for osteoporosis, marketed in Egypt by Hikma Pharma.

• Treatment of postmenopausal osteoporosis to reduce the risk of vertebral fractures; established postmenopausal osteoporosis to reduce hip fracture risk; osteoporosis in men at high risk of fractures.Population: Adultselectronic medicines compendium (eMC)
• Treatment and prevention of postmenopausal osteoporosis; to increase bone mass in men with osteoporosis; glucocorticoid-induced osteoporosis; Paget's disease (indications across ACTONEL strengths).Population: AdultsDailyMed (U.S. National Library of Medicine)

• Common: headache, constipation, dyspepsia, nausea, abdominal pain, diarrhoea, musculoskeletal pain. Uncommon: gastritis, oesophagitis, dysphagia, duodenitis, oesophageal ulcer, iritis. Post-marketing: hypersensitivity/skin reactions, osteonecrosis of the jaw, atypical femoral fractures.International label, equivalent formulation · electronic medicines compendium (eMC)

• Hypersensitivity to risedronate or excipients; hypocalcaemia; pregnancy and lactation; severe renal impairment (CrCl < 30 ml/min).International label, equivalent formulation · electronic medicines compendium (eMC)
• Oesophageal abnormalities delaying emptying (stricture, achalasia); inability to stand or sit upright for at least 30 minutes; hypocalcaemia; known hypersensitivity.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• Upper GI irritation (oesophagitis, gastritis, ulceration): caution in oesophageal disorders, inability to stay upright, or active/recent upper GI problems; stop and seek advice if dysphagia, painful swallowing or retrosternal pain occur.International label, equivalent formulation · electronic medicines compendium (eMC)
• Treat hypocalcaemia and other bone/mineral disturbances (e.g. parathyroid dysfunction, hypovitaminosis D) before or at the start of therapy.International label, equivalent formulation · electronic medicines compendium (eMC)
• Atypical femoral fractures with long-term bisphosphonate use; report thigh, hip or groin pain.International label, equivalent formulation · electronic medicines compendium (eMC)

• Polyvalent cations (calcium, magnesium, iron, aluminium)Interfere with risedronate absorption; take at different times.electronic medicines compendium (eMC)

• No adequate human data; animal studies show reproductive toxicity. Must not be used during pregnancy.International label, equivalent formulation · electronic medicines compendium (eMC)
• Small amounts pass into milk in animals; must not be used by breast-feeding women.International label, equivalent formulation · electronic medicines compendium (eMC)