دواعي استعمال روكورونيوم برومايد هاملن 50مجم/5مل 5 فيال وريدي

Rocuronium bromide 50 mg/5 ml solution for intravenous injection (hameln brand), pack of 5 vials; Egyptian distributor listed as Sunny Pharmaceuticals.

• Adjunct to general anaesthesia to facilitate rapid sequence and routine tracheal intubation, and to provide skeletal muscle relaxation during surgery or mechanical ventilation.DailyMed (U.S. National Library of Medicine)

• Most common adverse reactions in clinical trials (2%): transient hypotension and hypertension; also anaphylaxis, residual paralysis, myopathy and increased pulmonary vascular resistance described.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Known hypersensitivity (e.g. anaphylaxis) to rocuronium bromide or other neuromuscular blocking agents.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Use only where facilities for intubation, mechanical ventilation, oxygen therapy and an antagonist are immediately available.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Severe anaphylaxis has been reported; consider cross-reactivity among neuromuscular blocking agents.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Accidental administration can cause death (medication errors); must be accompanied by adequate anaesthesia or sedation; consider reversal where residual paralysis is likely.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Inhalation anaesthetics, certain antibiotics (e.g. aminoglycosides, vancomycin, tetracyclines), quinidine, magnesium, lithium, local anaesthetics, procainamideMay enhance rocuronium neuromuscular blocking activity.DailyMed (U.S. National Library of Medicine)
• AnticonvulsantsMay reduce rocuronium activity.DailyMed (U.S. National Library of Medicine)
• SuccinylcholineUse of rocuronium before succinylcholine has not been studied.DailyMed (U.S. National Library of Medicine)

• Decades of use and available data have not identified a drug-associated risk of major birth defects, miscarriage or adverse maternal/fetal outcomes; rocuronium crosses the placenta; not recommended for rapid sequence induction in Caesarean section.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• No data on presence in human milk or effects on the breastfed infant or milk production.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Dosing should be guided by clinical response and neuromuscular (train-of-four) monitoring.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)