دواعي استعمال Romacox 12.5 mg tablets

Romacox rofecoxib 12.5 mg oral tablets, pack of 10 (Apex Pharmaceuticals, Egypt).

• Relief of signs and symptoms of osteoarthritis.U.S. FDA (Drugs@FDA)
• Relief of signs and symptoms of rheumatoid arthritis in adults.U.S. FDA (Drugs@FDA)
• Management of acute pain in adults.U.S. FDA (Drugs@FDA)
• Treatment of primary dysmenorrhoea.U.S. FDA (Drugs@FDA)

• Known hypersensitivity to rofecoxib or any component; patients who had asthma, urticaria or allergic-type reactions after aspirin or other NSAIDs.نشرة دولية لنفس التركيبة · U.S. FDA (Drugs@FDA)

• Serious GI toxicity (bleeding, ulceration, perforation) can occur at any time; extreme caution with prior ulcer disease or GI bleeding.نشرة دولية لنفس التركيبة · U.S. FDA (Drugs@FDA)
• Anaphylactoid reactions and angioedema reported; do not give to patients with the aspirin triad.نشرة دولية لنفس التركيبة · U.S. FDA (Drugs@FDA)
• Not recommended in advanced renal disease; if used, monitor kidney function closely.نشرة دولية لنفس التركيبة · U.S. FDA (Drugs@FDA)
• The VIGOR study showed a higher incidence of adjudicated serious cardiovascular thrombotic events with rofecoxib 50 mg than with naproxen; rofecoxib is not a substitute for aspirin for cardiovascular prophylaxis.نشرة دولية لنفس التركيبة · U.S. FDA (Drugs@FDA)

• No studies in pregnant women; use only if the potential benefit justifies the potential risk to the fetus.نشرة دولية لنفس التركيبة · U.S. FDA (Drugs@FDA)
• Excreted in milk of lactating rats; unknown in humans; decide whether to discontinue nursing or the drug.نشرة دولية لنفس التركيبة · U.S. FDA (Drugs@FDA)