دواعي استعمال رومانتيجرا 20مجم 4 اقراص

Vardenafil 20 mg film-coated tablets, pack of 4, by Global Napi Pharmaceuticals / Global Advanced Pharmaceutical (GAP), Egypt.

• Treatment of erectile dysfunction.DailyMed (U.S. National Library of Medicine)

• Most common (at least 2%): headache, flushing, rhinitis/nasal congestion, dyspepsia, sinusitis, flu syndrome, dizziness, increased creatine kinase, nausea, back pain.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Use with nitrates (regularly or intermittently) or nitric oxide donors.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Use with guanylate cyclase stimulators such as riociguat.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Do not use if sexual activity is inadvisable because of cardiovascular status.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Seek immediate medical help for an erection lasting more than 4 hours (priapism).نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Stop and seek medical attention for sudden loss of vision (possible NAION) or sudden decrease or loss of hearing.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Caution with alpha-blockers (symptomatic hypotension); avoid in congenital QT prolongation or with class IA/III antiarrhythmics.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Nitrates / nitric oxide donorsContraindicated: potentiated hypotensive effect.DailyMed (U.S. National Library of Medicine)
• Alpha-blockersAdditive blood-pressure lowering; start vardenafil at 5 mg in patients stable on alpha-blocker therapy.DailyMed (U.S. National Library of Medicine)
• Strong/moderate CYP3A4 inhibitors (ritonavir, cobicistat, ketoconazole, itraconazole, clarithromycin, erythromycin, indinavir, saquinavir, atazanavir)Dose limits: ritonavir or cobicistat no more than 2.5 mg per 72 hours; indinavir, saquinavir, atazanavir, ketoconazole/itraconazole 400 mg, clarithromycin no more than 2.5 mg per 24 hours; ketoconazole/itraconazole 200 mg or erythromycin no more than 5 mg per 24 hours.DailyMed (U.S. National Library of Medicine)

• Not indicated for use in females; no human pregnancy data; no adverse developmental outcomes in rat and rabbit studies at high exposures.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Not indicated for use in females; no information on presence in human milk (present in rat milk).نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Selective inhibitor of cGMP-specific phosphodiesterase type 5.