سعر سانسو د3 2500 وحدة دولية 28 قرص 2026

Sanso D3 2500 IU tablets, pack of 28 (AUG Pharma, Egypt): a cholecalciferol (vitamin D3) supplement, 2500 IU per tablet, listed in Egypt for supporting bone health and preventing/correcting vitamin D deficiency.

• Excess vitamin D is toxic: it causes marked hypercalcaemia, hypercalciuria and high serum 25(OH)D, with nausea, vomiting, muscle weakness, neuropsychiatric disturbances, pain, loss of appetite, dehydration, polyuria, excessive thirst and kidney stones; extreme cases can cause renal failure, soft-tissue calcification, cardiac arrhythmias and death.General active-ingredient information · NIH Office of Dietary Supplements
• The Food and Nutrition Board noted that toxicity is unlikely at daily intakes below 10,000 IU (250 mcg), but that intakes even below the UL might have adverse effects over time; it advised avoiding serum 25(OH)D above about 125-150 nmol/L (50-60 ng/mL).General active-ingredient information · NIH Office of Dietary Supplements

• OrlistatOrlistat with a reduced-fat diet can reduce absorption of vitamin D from food and supplements.NIH Office of Dietary Supplements
• Statins (atorvastatin, lovastatin, simvastatin)Statins may reduce vitamin D synthesis; high vitamin D intakes might reduce the potency of these statins (shared metabolizing enzyme).NIH Office of Dietary Supplements
• Corticosteroids (e.g. prednisone)Corticosteroids can reduce calcium absorption and impair vitamin D metabolism.NIH Office of Dietary Supplements
• Thiazide diureticsThiazides decrease urinary calcium excretion; combined with vitamin D supplements they might cause hypercalcaemia, especially in older adults and people with impaired renal function or hyperparathyroidism.NIH Office of Dietary Supplements

• The vitamin D RDA in pregnancy is 600 IU (15 mcg)/day and the UL is 4,000 IU (100 mcg)/day (ages 14-50).General active-ingredient information · NIH Office of Dietary Supplements
• The vitamin D RDA during lactation is 600 IU (15 mcg)/day and the UL is 4,000 IU (100 mcg)/day; human milk alone usually does not meet an infant's vitamin D needs.General active-ingredient information · NIH Office of Dietary Supplements

• Serum 25(OH)D is the main indicator of vitamin D status; levels of 50 nmol/L (20 ng/mL) or more are adequate for most people and levels above 125 nmol/L (50 ng/mL) are linked to potential adverse effects.General active-ingredient information · NIH Office of Dietary Supplements

• Cholecalciferol (vitamin D3): Biologically inert until hydroxylated in the liver to 25(OH)D and in the kidney to active 1,25(OH)2D (calcitriol), which promotes intestinal calcium absorption and maintains serum calcium and phosphate for bone mineralization.