سعر سيمبرا جايد 10 كبسول 2024

• Relief of symptoms of seasonal allergic rhinitis (sneezing, rhinorrhoea, pruritus, lacrimation, nasal congestion) when both antihistamine and decongestant activity are desired.DailyMed (U.S. National Library of Medicine)

• Somnolence (about 12% vs 6% placebo in trials) and other sympathomimetic/antihistamine effects; see US label table.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Sensitivity to acrivastine, other alkylamine antihistamines, pseudoephedrine or other sympathomimetics; severe hypertension or severe coronary artery disease; MAO inhibitor use or within 14 days of stopping one.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Use with caution in hypertension, diabetes, ischaemic heart disease, increased intraocular pressure, hyperthyroidism, prostatic hypertrophy, stenosing peptic ulcer or pyloroduodenal obstruction; elderly are more prone to sympathomimetic adverse reactions.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Acrivastine is sedating in some patients; avoid alcohol and other CNS depressants and assess response before driving.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Use of the combination in renal impairment (creatinine clearance <= 48 mL/min) is not recommended; both components are renally excreted.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• MAO inhibitorsRisk of hypertensive crisis; do not use with or within 14 days after an MAO inhibitor.DailyMed (U.S. National Library of Medicine)
• Antihypertensives that interfere with sympathetic activityPseudoephedrine may reduce their antihypertensive effect.DailyMed (U.S. National Library of Medicine)
• Alcohol and other CNS depressantsAdditional reduction in alertness; avoid.DailyMed (U.S. National Library of Medicine)

• No adequate studies in pregnant women; use only if the potential benefit justifies the risk to the fetus.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Pseudoephedrine is excreted in milk (acrivastine unknown); use only if benefit justifies risk to the nursing infant.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

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