دواعي استعمال سيجدوتاستر 0.5مجم 10 كبسولات

Sigdutaster 0.5 mg capsules (dutasteride) by Sigma (Egypt), a 5-alpha-reductase inhibitor for symptomatic benign prostatic hyperplasia.

• Symptomatic BPH in men with an enlarged prostate: improve symptoms, reduce risk of acute urinary retention and BPH-related surgery (monotherapy).الفئة: Adult menDailyMed (U.S. National Library of Medicine)
• Symptomatic BPH in men with an enlarged prostate, in combination with tamsulosin.الفئة: Adult menDailyMed (U.S. National Library of Medicine)

• Most common (>=1%, more than placebo): impotence, decreased libido, ejaculation disorders, breast disorders.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Pregnancy (women who are pregnant).نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Clinically significant hypersensitivity (e.g. serious skin reactions, angioedema) to dutasteride or other 5-alpha-reductase inhibitors.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Reduces serum PSA by about 50%; any confirmed PSA increase on treatment should be evaluated for prostate cancer.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• May increase the risk of high-grade prostate cancer; exclude other urological conditions before treatment.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Absorbed through the skin: women and children should avoid contact with leaking capsules; men should not donate blood until 6 months after the last dose.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Potent chronic CYP3A4 inhibitors (e.g. ritonavir)Use with caution; dutasteride exposure may increase.DailyMed (U.S. National Library of Medicine)

• Contraindicated in pregnancy and not indicated for women; may cause abnormal development of male fetal genitalia; women who are or may become pregnant should not handle leaking capsules.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Not indicated for use in women; no data on presence in human milk.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• دوتاستيريد: Inhibits type 1 and type 2 5-alpha-reductase, preventing conversion of testosterone to dihydrotestosterone (US label).