دواعي استعمال Sigmacortin 500mg pd. for i.m./i.v.

Sigmacortin 500 mg powder for IM/IV injection (hydrocortisone sodium succinate) by Sigma-Tec / Sigma (Egypt), a systemic glucocorticoid for emergency and acute use when oral therapy is not feasible.

• IV/IM use when oral therapy is not feasible in corticosteroid-responsive conditions, e.g. severe allergic states (asthma, drug hypersensitivity, transfusion reactions), dermatologic, endocrine, rheumatic and other disorders listed in the label.الفئة: Adults and children (per label)DailyMed (U.S. National Library of Medicine)

• Reported with Solu-Cortef or other corticosteroids: hypersensitivity/anaphylaxis, leukocytosis, cardiovascular effects (arrhythmias, hypertension, heart failure, syncope), fluid/electrolyte, endocrine, musculoskeletal, GI, dermatologic and neuropsychiatric effects.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Systemic fungal infections; known hypersensitivity to the product or its constituents.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Intramuscular corticosteroids are contraindicated in idiopathic thrombocytopenic purpura; intrathecal administration is contraindicated.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Serious neurologic events (spinal cord infarction, paraplegia, stroke) reported with epidural corticosteroid injection; epidural use not approved.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Prolonged high-dose therapy may cause hypernatraemia; consider switching to a corticoid with little sodium retention when therapy continues beyond 48-72 hours.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Corticosteroids are teratogenic in many animal species (e.g. cleft palate); no adequate studies in pregnant women; use only if benefit justifies fetal risk; observe infants for hypoadrenalism.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Systemic corticosteroids appear in human milk and could suppress growth or endogenous corticosteroid production; decide whether to continue nursing or the drug.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)