سعر سوبوبيكسول 0.25مجم 10 اقراص 2022

Pramipexole 0.25 mg immediate-release oral tablets (Sobol El Dawa Misr, Egypt); non-ergot dopamine agonist for Parkinson's disease and restless legs syndrome.

• Treatment of Parkinson's disease.Population: AdultsDailyMed (U.S. National Library of Medicine)
• Treatment of moderate-to-severe primary Restless Legs Syndrome.Population: AdultsDailyMed (U.S. National Library of Medicine)

• Early PD: nausea, dizziness, somnolence, insomnia, constipation, asthenia, hallucinations.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Advanced PD with levodopa: postural hypotension, dyskinesia, extrapyramidal syndrome, insomnia, dizziness, hallucinations, confusion, constipation, dry mouth, amnesia, urinary frequency.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• RLS: nausea and somnolence.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• None (US label).International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Falling asleep during activities of daily living (including driving) and somnolence, sometimes without warning.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Symptomatic orthostatic hypotension, especially during dose escalation.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Impulse-control/compulsive behaviours (gambling, sexual urges, spending, binge eating).International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Dopamine antagonists (neuroleptics, metoclopramide)May diminish the effectiveness of pramipexole.DailyMed (U.S. National Library of Medicine)
• LevodopaWhen combined, a reduction of the levodopa dose should be considered.DailyMed (U.S. National Library of Medicine)

• No adequate data on developmental risk in pregnant women; postnatal growth inhibition in rats at clinically relevant exposures.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• No data on presence in human milk; inhibition of lactation is expected because pramipexole inhibits prolactin secretion.International label, same formulation · DailyMed (U.S. National Library of Medicine)