سعر سوماتوستاتين ليومارك 3مجم/3مل امبول 2022

Somatostatin Lyomark is a 3 mg somatostatin injectable product by Lyomark Pharma (Germany), imported to Egypt via EIMC and listed as a single 3 mg/3 ml ampoule; it is used in hospital as a continuous IV infusion for severe upper GI bleeding and pancreatic surgery complications.

• Severe acute bleeding from gastroduodenal ulcers.Population: AdultsAgencija za lekove i medicinska sredstva Srbije (ALIMS)
• Severe acute bleeding in acute erosive or haemorrhagic gastritis.Population: AdultsAgencija za lekove i medicinska sredstva Srbije (ALIMS)
• Prophylaxis of postoperative pancreatic complications after pancreatic surgery.Population: AdultsAgencija za lekove i medicinska sredstva Srbije (ALIMS)

• Uncommon: feeling of heat, abdominal pain, nausea, vomiting, diarrhoea, dizziness, generalised itching. Very rare: respiratory arrest (treatable), ventricular extrasystoles, water intoxication with hyponatraemia. Frequency unknown: thrombocytopenia, hypo-/hyperglycaemia, blood pressure rise with rapid infusion, reduced renal plasma flow and urine volume.International label, equivalent formulation · Agencija za lekove i medicinska sredstva Srbije (ALIMS)

• Hypersensitivity to the active substance or excipients.International label, equivalent formulation · Agencija za lekove i medicinska sredstva Srbije (ALIMS)
• Spurting arterial haemorrhage, which must be treated surgically.International label, equivalent formulation · Agencija za lekove i medicinska sredstva Srbije (ALIMS)

• Avoid repeated courses because sensitisation cannot be excluded.International label, equivalent formulation · Agencija za lekove i medicinska sredstva Srbije (ALIMS)
• Initially blood glucose may fall (glucagon inhibition), then rise after 2-3 hours (insulin inhibition); insulin-dependent diabetics may become hypoglycaemic if insulin is unchanged; avoid insulin-dependent sugars.International label, equivalent formulation · Agencija za lekove i medicinska sredstva Srbije (ALIMS)
• May reduce renal plasma flow, glomerular filtration and urine volume and increase urine osmolality.International label, equivalent formulation · Agencija za lekove i medicinska sredstva Srbije (ALIMS)

• BarbituratesSomatostatin prolongs barbiturate-induced sleeping time.Agencija za lekove i medicinska sredstva Srbije (ALIMS)
• PentetrazolSomatostatin enhances the effect of pentetrazol.Agencija za lekove i medicinska sredstva Srbije (ALIMS)
• PropranololMay enhance the somatostatin-related rise in blood glucose.Agencija za lekove i medicinska sredstva Srbije (ALIMS)

• Should not be used during pregnancy or the peri- and postnatal period.International label, equivalent formulation · Agencija za lekove i medicinska sredstva Srbije (ALIMS)
• Should not be used during breastfeeding.International label, equivalent formulation · Agencija za lekove i medicinska sredstva Srbije (ALIMS)

• Somatostatin: Synthetic tetradecapeptide identical to natural somatostatin; inhibits gastric acid, pepsin and gastrin secretion and exocrine pancreatic secretion, and reduces splanchnic blood flow (about 28% at 250 micrograms/hour) (Serbian SmPC 5.1).