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Sumatriptan oral tablets (triptan) listed in Egyptian price directories for acute migraine.

• Acute treatment of migraine with or without aura in adults (not for prevention; not established for cluster headache)الفئة: AdultsDailyMed (U.S. National Library of Medicine)

• Adverse reactions in placebo-controlled trials include paresthesia, warm/cold sensations, chest/neck/throat/jaw pain, tightness or pressure, and malaise/fatigue.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Ischemic coronary artery disease or coronary artery vasospasm, including Prinzmetal angina.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Wolff-Parkinson-White syndrome or arrhythmias associated with other cardiac accessory conduction pathway disorders.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• History of stroke or transient ischemic attack, or hemiplegic or basilar migraine.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Peripheral vascular disease or ischemic bowel disease.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Uncontrolled hypertension.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Use within 24 hours of an ergotamine-containing or ergot-type medication or another 5-HT1 agonist.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Concurrent use of, or use within 2 weeks of, an MAO-A inhibitor.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Hypersensitivity to sumatriptan (angioedema and anaphylaxis seen).نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Severe hepatic impairment.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Serious cardiac events (myocardial ischemia/infarction, Prinzmetal angina, arrhythmias) can occur; evaluate patients with cardiovascular risk factors before use.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Serotonin syndrome may occur, particularly with SSRIs, SNRIs, TCAs or MAO inhibitors.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Significant blood pressure elevation, including hypertensive crisis, has been reported.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Overuse of acute migraine drugs on 10 or more days per month may cause medication overuse headache.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Ergot-containing drugsAdditive vasospastic effects; use within 24 hours is contraindicated.DailyMed (U.S. National Library of Medicine)
• MAO-A inhibitorsIncrease systemic exposure to sumatriptan; concurrent use or use within 2 weeks is contraindicated.DailyMed (U.S. National Library of Medicine)
• Other 5-HT1 agonists (triptans)Additive vasospastic effects; use within 24 hours of each other is contraindicated.DailyMed (U.S. National Library of Medicine)
• SSRIs, SNRIs, TCAsCases of serotonin syndrome reported during coadministration with triptans.DailyMed (U.S. National Library of Medicine)

• Pregnancy registry and epidemiological data have not detected an increased frequency or consistent pattern of birth defects; animal studies showed embryolethality and fetal abnormalities.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Sumatriptan is excreted in human milk after subcutaneous administration; infant exposure can be minimised by avoiding breastfeeding for 12 hours after treatment.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Consider cardiovascular evaluation in triptan-naive patients with multiple cardiovascular risk factors before use.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Agonist at 5-HT1B/1D receptors on intracranial blood vessels and trigeminal sensory nerves, causing cranial vessel constriction and inhibition of pro-inflammatory neuropeptide release (US label).