دواعي استعمال سوبران 100% سائل الاستنشاق
معلومات من نشرات دوائية ومراجع موثقة، مع مصدر كل معلومة. السعر الحالي: 1,500ج.م.
عن الدواء
Desflurane 100% volatile liquid for inhalation (240 ml bottle), a halogenated general anaesthetic for use by anaesthesia professionals with a dedicated vaporizer.
دواعي الاستعمال
- Induction and/or maintenance of anaesthesia in adultsالفئة: AdultsDailyMed (U.S. National Library of Medicine)
- Maintenance of anaesthesia in intubated paediatric patients after induction with other agentsالفئة: Paediatric (intubated)DailyMed (U.S. National Library of Medicine)
موانع الاستعمال
- Known or suspected genetic susceptibility to malignant hyperthermia; patients in whom general anaesthesia is contraindicated; induction of anaesthesia in paediatric patients; known sensitivity to desflurane or other halogenated agents.نشرة دولية لنفس المنتج · DailyMed (U.S. National Library of Medicine)
تحذيرات واحتياطات
- Malignant hyperthermia may be triggered; risk increases with concomitant succinylcholine; fatal outcomes reported.نشرة دولية لنفس المنتج · DailyMed (U.S. National Library of Medicine)
- Perioperative hyperkalaemia with arrhythmias and death reported in paediatric patients, especially with neuromuscular disease (e.g. Duchenne muscular dystrophy) and concomitant succinylcholine.نشرة دولية لنفس المنتج · DailyMed (U.S. National Library of Medicine)
- QT prolongation with torsade de pointes has been reported; monitor cardiac rhythm in susceptible patients.نشرة دولية لنفس المنتج · DailyMed (U.S. National Library of Medicine)
- May cause sensitivity hepatitis in patients sensitised by previous halogenated anaesthetic exposure.نشرة دولية لنفس المنتج · DailyMed (U.S. National Library of Medicine)
- Not approved for maintenance in non-intubated children because of high rates of respiratory adverse reactions (coughing 26%, laryngospasm 13%).نشرة دولية لنفس المنتج · DailyMed (U.S. National Library of Medicine)
الحمل والرضاعة
- No adequate well-controlled studies in pregnant women; embryo-fetal toxicity seen in rats and rabbits at 1 MAC for 4 h/day during organogenesis.نشرة دولية لنفس المنتج · DailyMed (U.S. National Library of Medicine)
- Not known whether excreted in human milk; use caution in nursing women.نشرة دولية لنفس المنتج · DailyMed (U.S. National Library of Medicine)
المتابعة أثناء العلاج
- Monitor cardiac rhythm in patients susceptible to QT prolongation.نشرة دولية لنفس المنتج · DailyMed (U.S. National Library of Medicine)
المصادر
- السعر: قوائم أسعار الأدوية المنشورة في مصر.
- DailyMed (U.S. National Library of Medicine)
- WHO Collaborating Centre for Drug Statistics Methodology
- PubChem (NCBI)