دواعي استعمال سوبرانيل 25مجم 20 كبسولة

Clomipramine 25 mg hard capsules, a tricyclic antidepressant, pack of 20 capsules.

• Treatment of obsessions and compulsions in obsessive-compulsive disorder (OCD)DailyMed (U.S. National Library of Medicine)

• Common: dry mouth, constipation, nausea, dyspepsia, anorexia, somnolence, tremor, dizziness, nervousness, myoclonus, changed libido, ejaculatory failure, impotence, micturition disorder, fatigue, sweating.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Hypersensitivity to clomipramine or other tricyclic antidepressants.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Use with MAOIs intended to treat psychiatric disorders, or within 14 days of stopping either drug, is contraindicated.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Boxed warning: antidepressants increased the risk of suicidal thinking and behaviour in children, adolescents and young adults in short-term studies.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Seizure was the most significant risk in premarket evaluation; cumulative incidence rises with dose and duration (1.45% at 365 days at doses up to 300 mg/day).نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Abrupt discontinuation may cause withdrawal symptoms (dizziness, nausea, vomiting, headache, malaise, sleep disturbance, hyperthermia, irritability).نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Monoamine oxidase inhibitorsContraindicated together or within 14 days.DailyMed (U.S. National Library of Medicine)
• Other CNS-active drugsCaution advised when used concomitantly.DailyMed (U.S. National Library of Medicine)

• No teratogenic effects in rats and mice up to 100 mg/kg; slight nonspecific embryo/fetotoxic effects in treated rodents.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Clomipramine is found in human milk; decide whether to discontinue nursing or the drug.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Monitor patients for clinical worsening, suicidality and unusual changes in behaviour, especially at the start of therapy and at dose changes.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)