دواعي استعمال سينتوسينون 5 وحدات دولية/مل 5 امبولات

Synthetic oxytocin 5 IU/ml injection ampoules for intramuscular/intravenous use in obstetrics.

• Induction of labour for medical reasons and stimulation of labour in hypotonic uterine inertia (antepartum).الفئة: Pregnant/postpartum womenelectronic medicines compendium (emc)
• Prevention and treatment of postpartum uterine atony and haemorrhage; use during caesarean section after delivery of the child.الفئة: Pregnant/postpartum womenelectronic medicines compendium (emc)

• Uterine hyperstimulation/tetanic contractions, uterine rupture, fetal distress, hypotension, tachycardia, QTc prolongation, water intoxication, and rarely postpartum DIC.نشرة دولية لتركيبة مكافئة · electronic medicines compendium (emc)

• Hypersensitivity; hypertonic uterine contractions, mechanical obstruction to delivery, fetal distress; conditions where vaginal delivery is inadvisable (e.g. cephalopelvic disproportion, malpresentation, placenta praevia, abruption, cord prolapse, uterine scar from major surgery); within 6 hours of vaginal prostaglandins.نشرة دولية لتركيبة مكافئة · electronic medicines compendium (emc)

• IV bolus may cause acute hypotension with flushing and reflex tachycardia; caution in cardiovascular disease and long-QT syndrome or QT-prolonging drugs.نشرة دولية لتركيبة مكافئة · electronic medicines compendium (emc)
• High doses with large volumes of electrolyte-free fluid can cause water intoxication with maternal and neonatal hyponatraemia; overstimulation may cause fetal distress or uterine rupture.نشرة دولية لتركيبة مكافئة · electronic medicines compendium (emc)

• Not expected to present a risk of fetal abnormalities when used as indicated, based on wide experience.نشرة دولية لتركيبة مكافئة · electronic medicines compendium (emc)
• Small quantities may pass into breast milk but are rapidly inactivated in the infant gut; not expected to harm the newborn.نشرة دولية لتركيبة مكافئة · electronic medicines compendium (emc)

• Monitor frequency, strength and duration of contractions and fetal heart rate throughout infusion; stop immediately with uterine hyperactivity or fetal distress.نشرة دولية لتركيبة مكافئة · electronic medicines compendium (emc)