دواعي استعمال تالوبرام 40مجم 30 اقراص

Citalopram 40 mg film-coated tablets (Adwia), a selective serotonin reuptake inhibitor (SSRI) antidepressant.

• Treatment of major depressive disorder (MDD) in adults.الفئة: AdultsDailyMed (U.S. National Library of Medicine)

• Use with, or within 14 days of stopping, MAOIs (including linezolid or intravenous methylene blue) because of serotonin syndrome risk.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Concomitant pimozide (risk of QT prolongation).نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Known hypersensitivity to citalopram or any inactive ingredient (angioedema and anaphylaxis reported).نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Boxed warning: antidepressants increased the risk of suicidal thoughts and behaviors in pediatric and young adult patients; monitor all patients for clinical worsening and emergence of suicidality.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Dose-dependent QTc prolongation, torsade de pointes, ventricular tachycardia and sudden death; avoid in congenital long QT syndrome, bradycardia, hypokalemia/hypomagnesemia, recent MI or uncompensated heart failure; discontinue if QTc persistently > 500 ms.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Serotonin syndrome, increased bleeding risk with aspirin/NSAIDs/anticoagulants, activation of mania, discontinuation syndrome, seizures, angle-closure glaucoma, hyponatremia and sexual dysfunction.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• MAOIs (incl. linezolid, IV methylene blue)Increased risk of serotonin syndrome; contraindicated.DailyMed (U.S. National Library of Medicine)
• PimozideIncreases pimozide concentrations and risk of QT prolongation; contraindicated.DailyMed (U.S. National Library of Medicine)

• Published data have not established an increased risk of major birth defects or miscarriage with citalopram; SSRI exposure in the month before delivery is associated with a less than 2-fold increased risk of postpartum hemorrhage.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Citalopram is present in human milk (relative infant dose 0.7-9.4%); irritability, restlessness, excessive somnolence, decreased feeding and weight loss reported in breastfed infants; monitor the infant.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Monitor electrolytes (potassium, magnesium) in patients at risk of hypokalemia or hypomagnesemia; monitor for clinical worsening and suicidality.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Blocks serotonin reuptake at the presynaptic neuron, potentiating serotonergic activity in the CNS.