دواعي استعمال تارجوفلوكساسين 750مجم 5 قرص

Levofloxacin 750 mg film-coated tablets, 5 film-coated tablets (1 strip), by Global Napi Pharmaceuticals (Egypt); fluoroquinolone antibacterial.

• Nosocomial pneumonia; community-acquired pneumonia (750 mg 5-day regimen); complicated skin and skin structure infections.الفئة: AdultsDailyMed (U.S. National Library of Medicine)
• Complicated urinary tract infections and acute pyelonephritis (750 mg once daily for 5 days).الفئة: AdultsDailyMed (U.S. National Library of Medicine)
• Inhalational anthrax (post-exposure) and plague; acute bacterial sinusitis and acute bacterial exacerbation of chronic bronchitis (reserve for patients without alternatives for the latter two and uncomplicated UTI).الفئة: Adults and pediatric patients where indicatedDailyMed (U.S. National Library of Medicine)

• Most common (>=3%): nausea, headache, diarrhea, insomnia, constipation and dizziness.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Known hypersensitivity to levofloxacin or other quinolone antibacterials.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Boxed warning: disabling and potentially irreversible serious adverse reactions (tendinitis/tendon rupture, peripheral neuropathy, CNS effects) and exacerbation of myasthenia gravis; discontinue immediately if they occur.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Serious hypersensitivity, hepatotoxicity, aortic aneurysm/dissection, C. difficile-associated diarrhea, QT prolongation, blood glucose disturbances and photosensitivity are labeled risks.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Multivalent cations (antacids, sucralfate, iron, zinc multivitamins, didanosine)Reduced levofloxacin absorption; separate by at least 2 hours.DailyMed (U.S. National Library of Medicine)
• WarfarinAnticoagulant effect may be enhanced; monitor PT/INR and bleeding.DailyMed (U.S. National Library of Medicine)
• Antidiabetic agentsDysglycemia; monitor blood glucose carefully.DailyMed (U.S. National Library of Medicine)

• Published human data have not identified a drug-associated risk of major birth defects, miscarriage or adverse maternal/fetal outcomes; no teratogenicity in rats and rabbits.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Levofloxacin is present in human milk; a lactating woman may pump and discard milk during treatment and for 2 days after the last dose, or breastfeeding is not recommended.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Monitor blood glucose in diabetic patients on antidiabetic agents and PT/INR with warfarin; renal function guides dosing.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• ليفوفلوكساسين: Inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV.