دواعي استعمال تارجوماش 80مجم 30 قرص
معلومات من نشرات دوائية ومراجع موثقة، مع مصدر كل معلومة. السعر الحالي: 75ج.م.
عن الدواء
Valsartan 80 mg film-coated tablets, 30 tablets (3 strips), by Mash Premiere (Egypt); angiotensin II receptor blocker.
دواعي الاستعمال
- Hypertension, to lower blood pressure.الفئة: Adults and children 1 year and olderDailyMed (U.S. National Library of Medicine)
- Heart failure (NYHA II-IV), to reduce hospitalization for heart failure.الفئة: AdultsDailyMed (U.S. National Library of Medicine)
- Post-myocardial infarction with left ventricular failure/dysfunction, to reduce cardiovascular mortality.الفئة: AdultsDailyMed (U.S. National Library of Medicine)
الآثار الجانبية
- Hypertension: headache, dizziness, viral infection, fatigue, abdominal pain. Heart failure: dizziness, hypotension, diarrhea, arthralgia, back pain, fatigue, hyperkalemia.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
موانع الاستعمال
- Known hypersensitivity to any component.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
- Do not coadminister aliskiren in patients with diabetes.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
تحذيرات واحتياطات
- Boxed warning (fetal toxicity): drugs acting on the renin-angiotensin system can cause fetal injury and death; discontinue as soon as pregnancy is detected.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
- Hypotension in volume- or salt-depleted patients; monitor renal function and serum potassium in susceptible patients.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
التداخلات الدوائية
- Potassium-sparing diuretics, potassium supplements, potassium salt substitutes, heparinIncreased serum potassium (and creatinine in heart failure); monitor potassium.DailyMed (U.S. National Library of Medicine)
- NSAIDs including COX-2 inhibitorsRisk of renal function deterioration and reduced antihypertensive effect.DailyMed (U.S. National Library of Medicine)
- LithiumIncreased serum lithium and lithium toxicity; monitor lithium levels.DailyMed (U.S. National Library of Medicine)
- Aliskiren / dual RAS blockadeIncreased risk of renal impairment, hypotension and hyperkalemia; aliskiren contraindicated with valsartan in diabetes.DailyMed (U.S. National Library of Medicine)
الحمل والرضاعة
- Use of RAS-acting drugs in the second and third trimesters reduces fetal renal function and increases fetal and neonatal morbidity and death; oligohydramnios reported with valsartan.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
- No human data; valsartan is present in rat milk; breastfeeding is not recommended during treatment.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
المتابعة أثناء العلاج
- Monitor blood pressure, renal function and serum potassium (and electrolytes with the HCTZ component) in susceptible patients.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
كيف يعمل الدواء
- فالسارتان: Blocks binding of angiotensin II to the AT1 receptor, inhibiting its vasoconstrictor and aldosterone-secreting effects.
المصادر
- السعر: قوائم أسعار الأدوية المنشورة في مصر.
- DailyMed (U.S. National Library of Medicine)
- WHO Collaborating Centre for Drug Statistics Methodology