دواعي استعمال تارجوماش كومب16012.5مجم 30 قرص

Valsartan 160 mg + hydrochlorothiazide 12.5 mg film-coated tablets, 30 tablets (3 strips), by Mash Premiere (Egypt).

• Hypertension, to lower blood pressure.الفئة: AdultsDailyMed (U.S. National Library of Medicine)

• Most common reasons for discontinuation were headache and dizziness; nasopharyngitis was the only adverse event >=2% and more frequent than placebo.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Hypersensitivity to any component; anuria; hypersensitivity to other sulfonamide-derived drugs.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Do not coadminister aliskiren in patients with diabetes.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Boxed warning (fetal toxicity): drugs acting on the renin-angiotensin system can cause fetal injury and death; discontinue as soon as pregnancy is detected.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Hypotension in volume- or salt-depleted patients; monitor renal function and serum potassium in susceptible patients.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• HCTZ component: fluid/electrolyte imbalance, exacerbation or activation of systemic lupus erythematosus, and acute angle-closure glaucoma/myopia.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Potassium-sparing diuretics, potassium supplements, potassium salt substitutes, heparinIncreased serum potassium (and creatinine in heart failure); monitor potassium.DailyMed (U.S. National Library of Medicine)
• NSAIDs including COX-2 inhibitorsRisk of renal function deterioration and reduced antihypertensive effect.DailyMed (U.S. National Library of Medicine)
• LithiumIncreased serum lithium and lithium toxicity; monitor lithium levels.DailyMed (U.S. National Library of Medicine)
• Aliskiren / dual RAS blockadeIncreased risk of renal impairment, hypotension and hyperkalemia; aliskiren contraindicated with valsartan in diabetes.DailyMed (U.S. National Library of Medicine)

• Use of RAS-acting drugs in the second and third trimesters reduces fetal renal function and increases fetal and neonatal morbidity and death; oligohydramnios reported with valsartan.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Valsartan is present in rat milk and hydrochlorothiazide is present in human milk; breastfeeding is not recommended during treatment.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Monitor blood pressure, renal function and serum potassium (and electrolytes with the HCTZ component) in susceptible patients.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)