دواعي استعمال تاريفلوكس 400 مجم 10 اقراص

Ofloxacin 400 mg tablets, 10 tablets (2 strips), by Borg (Egypt); fluoroquinolone antibacterial.

• Mild to moderate infections due to susceptible bacteria: acute bacterial exacerbation of chronic bronchitis (reserve), community-acquired pneumonia, uncomplicated skin and skin structure infections.الفئة: AdultsDailyMed (U.S. National Library of Medicine)
• Uncomplicated urethral/cervical gonorrhea, nongonococcal urethritis/cervicitis (C. trachomatis), acute pelvic inflammatory disease, uncomplicated cystitis (reserve), complicated UTI, prostatitis due to E. coli.الفئة: AdultsDailyMed (U.S. National Library of Medicine)

• Drug-related in trials: nausea 3%, insomnia 3%, headache, dizziness, diarrhea, vomiting, rash, pruritus, external genital pruritus and vaginitis (about 1% each).نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• History of hypersensitivity to ofloxacin or any member of the quinolone group.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Boxed warning: disabling and potentially irreversible tendinitis/tendon rupture, peripheral neuropathy and CNS effects; may exacerbate myasthenia gravis; reserve for ABECB and uncomplicated cystitis when no alternatives exist.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Ofloxacin increased the incidence and severity of osteochondrosis in immature rats; other quinolones produce arthropathy in immature animals.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Antacids, sucralfate, metal cations, zinc multivitamins, didanosineChelation markedly reduces absorption; avoid within 2 hours of the dose.DailyMed (U.S. National Library of Medicine)
• CyclosporineElevated cyclosporine levels reported with other quinolones; not studied for ofloxacin.DailyMed (U.S. National Library of Medicine)

• No teratogenicity in rats and rabbits at high doses; fetotoxic at high doses; no adequate studies in pregnant women; use only if benefit justifies risk.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• أوفلوكساسين: Inhibits bacterial DNA gyrase and topoisomerase IV.