دواعي استعمال تازوكس 50مجم 30 اقراص

Cilostazol 50 mg tablets, pack of 30 (3 strips), by Rameda (Egypt); phosphodiesterase-3 inhibitor used for intermittent claudication.

• Reduction of symptoms of intermittent claudication (increased walking distance)الفئة: AdultsDailyMed (U.S. National Library of Medicine)

• Most common (>=2% and twice placebo at 100 mg twice daily): headache, diarrhea, abnormal stools, palpitation.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Heart failure of any severity (PDE III inhibitors decreased survival in class III-IV heart failure).نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Hypersensitivity to cilostazol or any tablet component.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• May induce tachycardia, palpitation, tachyarrhythmia or hypotension; risk of angina exacerbation or MI in ischemic heart disease.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Left ventricular outflow tract obstruction reported with sigmoid-shaped septum.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Thrombocytopenia or leukopenia progressing to agranulocytosis; monitor counts.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Avoid in hemostatic disorders or active pathologic bleeding.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Strong/moderate CYP3A4 inhibitors (ketoconazole, itraconazole, erythromycin, diltiazem, grapefruit juice)Increase cilostazol exposure; reduce dose to 50 mg twice daily.DailyMed (U.S. National Library of Medicine)
• CYP2C19 inhibitors (ticlopidine, fluconazole, omeprazole)Increase exposure to active metabolites; reduce dose to 50 mg twice daily.DailyMed (U.S. National Library of Medicine)

• Teratogenic in rats at doses >5 times MRHD; no adequate studies in pregnant women.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Transfer into milk reported in rats; discontinue nursing or discontinue cilostazol.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Monitor platelet and white blood cell counts.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)