دواعي استعمال تلفاست 180مجم 20 قرص

Fexofenadine hydrochloride 180 mg film-coated tablets, pack of 20 (Sanofi, Egypt); second-generation non-sedating H1 antihistamine.

• Relief of symptoms associated with chronic idiopathic urticaria in adults and children 12 years and older.الفئة: Adults and children >=12 yearselectronic medicines compendium (emc, medicines.org.uk; MHRA-authorised)
• Temporary relief of hay fever/upper respiratory allergy symptoms (runny nose, sneezing, itchy watery eyes, itchy nose or throat) (US OTC).DailyMed (U.S. National Library of Medicine)

• Common: headache, drowsiness, dizziness, nausea; uncommon: fatigue; blurred vision frequency not known.نشرة دولية لنفس التركيبة · electronic medicines compendium (emc, medicines.org.uk; MHRA-authorised)

• Hypersensitivity to the active substance or any excipient.نشرة دولية لنفس التركيبة · electronic medicines compendium (emc, medicines.org.uk; MHRA-authorised)

• Limited data in the elderly and in renal or hepatic impairment; use with care in these groups.نشرة دولية لنفس التركيبة · electronic medicines compendium (emc, medicines.org.uk; MHRA-authorised)
• Patients with history of or ongoing cardiovascular disease should be warned that antihistamines as a class have been associated with tachycardia and palpitations.نشرة دولية لنفس التركيبة · electronic medicines compendium (emc, medicines.org.uk; MHRA-authorised)
• Ask a doctor before use if you have kidney disease; do not take with aluminium or magnesium antacids or with fruit juices.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• P-gp inhibitors (erythromycin, ketoconazole)Co-administration raised fexofenadine plasma levels 2-3 fold without QT effects or increased adverse reactions.electronic medicines compendium (emc, medicines.org.uk; MHRA-authorised)
• ApalutamideWeak P-gp inducer; decreased fexofenadine AUC by about 30%.electronic medicines compendium (emc, medicines.org.uk; MHRA-authorised)
• Aluminium/magnesium hydroxide antacidsAntacid reduces fexofenadine bioavailability; separate administration (UK SmPC; section text partly read).electronic medicines compendium (emc, medicines.org.uk; MHRA-authorised)

• No adequate data in pregnant women; limited animal studies show no harm; should not be used during pregnancy unless clearly necessary.نشرة دولية لنفس التركيبة · electronic medicines compendium (emc, medicines.org.uk; MHRA-authorised)
• No human milk data; fexofenadine crossed into breast milk when terfenadine was given; use while breast-feeding is not recommended per the SmPC (text partly read).نشرة دولية لنفس التركيبة · electronic medicines compendium (emc, medicines.org.uk; MHRA-authorised)

• فيكسوفينادين: Non-sedating selective peripheral H1-receptor antagonist (UK SmPC 5.1).