دواعي استعمال تنتافير 80 مكجم/ للاستنشاق 120 جرعة

معلومات من نشرات دوائية ومراجع موثقة، مع مصدر كل معلومة. السعر الحالي: 98ج.م.

دواعي الاستعمال

Treatment to control persistent asthma in adults and adolescents (12 years and older).الفئة: Adults and adolescents 12 years and olderelectronic medicines compendium (emc, medicines.org.uk; MHRA-authorised)
Maintenance treatment of asthma as prophylactic therapy in patients 12 years and older; not for relief of acute bronchospasm.الفئة: 12 years and olderDailyMed (U.S. National Library of Medicine)

الآثار الجانبية

About 5% of patients had adverse reactions in trials, mostly mild; uncommon/rare effects include application-site reactions and dryness, oral fungal infections, bad taste, nausea, palpitations, hypersensitivity and angioedema.نشرة دولية لنفس التركيبة · electronic medicines compendium (emc, medicines.org.uk; MHRA-authorised)

موانع الاستعمال

Hypersensitivity to ciclesonide or to any of the excipients.نشرة دولية لنفس التركيبة · electronic medicines compendium (emc, medicines.org.uk; MHRA-authorised)
Primary treatment of status asthmaticus or other acute episodes of asthma where intensive measures are required.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)

تحذيرات واحتياطات

Not for relief of acute asthma symptoms (use a short-acting bronchodilator); use with caution in active or quiescent pulmonary tuberculosis or fungal, viral or bacterial infections.نشرة دولية لنفس التركيبة · electronic medicines compendium (emc, medicines.org.uk; MHRA-authorised)
Oropharyngeal candidiasis, immunosuppression/infection risk, hypercorticism and adrenal suppression, reduced bone mineral density, glaucoma/cataracts and paradoxical bronchospasm have been reported with inhaled corticosteroids including ciclesonide.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)

التداخلات الدوائية

Ketoconazole and other potent CYP3A4 inhibitorsOral ketoconazole increased exposure to the active metabolite des-ciclesonide; caution with potent CYP3A4 inhibitors.DailyMed (U.S. National Library of Medicine)

الحمل والرضاعة

No adequate and well-controlled studies in pregnant women; use only if the potential benefit to the mother justifies the potential risk to the fetus, at the lowest effective dose.نشرة دولية لنفس التركيبة · electronic medicines compendium (emc, medicines.org.uk; MHRA-authorised)

المتابعة أثناء العلاج

Monitor patients with vision change or history of raised intraocular pressure, glaucoma or cataracts; monitor bone mineral density risk factors per standard care.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)

كيف يعمل الدواء

سيكليسونيد: Prodrug with low glucocorticoid-receptor affinity, converted by esterases in the lung to the active metabolite des-ciclesonide, which has anti-inflammatory activity (UK Alvesco SmPC 5.1).

المصادر