دواعي استعمال ثيرازوليد 600مجم 20 قرص

Linezolid 600 mg film-coated tablets, pack of 20 (Tabuk Pharma, manufactured by EGPI, Egypt); oxazolidinone antibacterial.

• Nosocomial pneumonia caused by susceptible Gram-positive bacteriaالفئة: Adults and childrenDailyMed (U.S. NLM)
• Community-acquired pneumonia caused by susceptible Gram-positive bacteriaالفئة: Adults and childrenDailyMed (U.S. NLM)
• Complicated skin and skin structure infections, including diabetic foot infections without concomitant osteomyelitisالفئة: Adults and childrenDailyMed (U.S. NLM)
• Uncomplicated skin and skin structure infectionsالفئة: Adults and childrenDailyMed (U.S. NLM)
• Vancomycin-resistant Enterococcus faecium infectionsالفئة: Adults and childrenDailyMed (U.S. NLM)

• Known hypersensitivity to linezolid or any other product component.نشرة دولية لنفس التركيبة · DailyMed (U.S. NLM)
• Patients taking any monoamine oxidase A or B inhibitor (e.g. phenelzine, isocarboxazid) or within two weeks of taking one.نشرة دولية لنفس التركيبة · DailyMed (U.S. NLM)

• Myelosuppression (anemia, leukopenia, pancytopenia, thrombocytopenia) may occur; monitor complete blood counts weekly.نشرة دولية لنفس التركيبة · DailyMed (U.S. NLM)
• Peripheral and optic neuropathy reported, primarily with treatment longer than 28 days; prompt ophthalmic evaluation if visual symptoms occur.نشرة دولية لنفس التركيبة · DailyMed (U.S. NLM)
• Serotonin syndrome with serotonergic agents; monitor and consider discontinuation if signs occur.نشرة دولية لنفس التركيبة · DailyMed (U.S. NLM)
• Clostridioides difficile-associated diarrhea; evaluate if diarrhea occurs.نشرة دولية لنفس التركيبة · DailyMed (U.S. NLM)
• Potential interactions producing elevation of blood pressure; monitor blood pressure.نشرة دولية لنفس التركيبة · DailyMed (U.S. NLM)
• Hypoglycemia in diabetic patients on insulin or oral hypoglycemic agents; hyponatremia/SIADH; rhabdomyolysis have been reported.نشرة دولية لنفس التركيبة · DailyMed (U.S. NLM)
• Not indicated for Gram-negative infections.نشرة دولية لنفس التركيبة · DailyMed (U.S. NLM)

• Monoamine oxidase inhibitorsContraindicated during or within two weeks of MAOI use.DailyMed (U.S. NLM)
• Serotonergic agentsRisk of serotonin syndrome; monitor.DailyMed (U.S. NLM)

• Published and postmarketing case reports have not identified a drug-associated risk of major birth defects, miscarriage or adverse maternal or fetal outcomes; embryo-fetal lethality seen in mice at 6.5 times human exposure.نشرة دولية لنفس التركيبة · DailyMed (U.S. NLM)
• Linezolid is present in breast milk (infant dose about 6-9% of the therapeutic infant dose); monitor breastfed infants for diarrhea and vomiting.نشرة دولية لنفس التركيبة · DailyMed (U.S. NLM)

• Complete blood counts weekly; serum sodium in patients at risk of hyponatremia; blood pressure where pressor interactions are possible.نشرة دولية لنفس التركيبة · DailyMed (U.S. NLM)