دواعي استعمال ثيولكان 600مجم 10 اقراص

Oral tablet containing thioctic acid (alpha-lipoic acid) 600 mg, marketed in Egypt by Hikma Pharma; listed in Egyptian directories as an antioxidant.

• Paraesthesia (abnormal sensations) in diabetic polyneuropathyالفئة: AdultsFachinfo-Service (fachinfo.de), Germany

• Common: dizziness. Very rare: allergic reactions (rash, urticaria, itching), hypoglycaemia, taste disturbance, headache, hyperhidrosis. Frequency not known: insulin autoimmune syndrome.نشرة دولية لتركيبة مكافئة · Fachinfo-Service (fachinfo.de), Germany

• Hypersensitivity to thioctic acid or to any of the excipients.نشرة دولية لتركيبة مكافئة · Fachinfo-Service (fachinfo.de), Germany

• Cases of insulin autoimmune syndrome (IAS) have been reported during thioctic acid treatment, more likely in carriers of certain HLA alleles (e.g. HLA-DRB1*04:06, *04:03); consider IAS in spontaneous hypoglycaemia.نشرة دولية لتركيبة مكافئة · Fachinfo-Service (fachinfo.de), Germany
• A changed urine odour may be noticed; it has no clinical relevance.نشرة دولية لتركيبة مكافئة · Fachinfo-Service (fachinfo.de), Germany

• CisplatinLoss of cisplatin efficacy with concomitant thioctic acid.Fachinfo-Service (fachinfo.de), Germany
• Metal-containing products (iron, magnesium, dairy calcium)Thioctic acid is a metal chelator; do not take together; iron/magnesium products can be taken at midday or evening when thioctic acid is taken 30 minutes before breakfast.Fachinfo-Service (fachinfo.de), Germany
• Insulin / oral antidiabeticsBlood-glucose-lowering effect may be enhanced; monitor glucose.Fachinfo-Service (fachinfo.de), Germany

• Animal studies showed no direct or indirect harmful effects on reproduction; use in pregnancy only after careful benefit-risk assessment.نشرة دولية لتركيبة مكافئة · Fachinfo-Service (fachinfo.de), Germany
• It is not known whether thioctic acid/metabolites pass into breast milk; decide whether to stop breastfeeding or to stop/abstain from therapy.نشرة دولية لتركيبة مكافئة · Fachinfo-Service (fachinfo.de), Germany

• Monitor blood glucose regularly, especially at the start of treatment in patients on insulin or oral antidiabetics; dose reduction of the antidiabetic may be needed.نشرة دولية لتركيبة مكافئة · Fachinfo-Service (fachinfo.de), Germany