دواعي استعمال ثيوبنتال 0.5 جم فيال 500 مجم

Thiopental sodium 500 mg vial for intravenous injection (barbiturate general anaesthetic), listed in Egypt under Sandoz > Novartis.

• Induction of general anaesthesia and adjunct to provide hypnosis during balanced anaesthesiaelectronic medicines compendium (emc), UK
• Adjunct for control of refractory convulsive disorders, including those caused by local anaestheticselectronic medicines compendium (emc), UK
• Reduction of raised intracranial pressure when controlled ventilation is providedelectronic medicines compendium (emc), UK

• Arrhythmia, myocardial depression, hypotension; respiratory depression, bronchospasm, laryngospasm, coughing; somnolence, delayed waking, headache, confusion, amnesia; shivering, thrombosis, phlebitis, injection-site pain; hypo-/hyperkalaemia; anaphylactoid/allergic reactions; nausea, vomiting.نشرة دولية لنفس التركيبة · electronic medicines compendium (emc), UK

• Hypersensitivity to barbiturates or excipients; respiratory obstruction, acute asthma, severe shock, dystrophia myotonica; porphyria (any barbiturate).نشرة دولية لنفس التركيبة · electronic medicines compendium (emc), UK

• Causes respiratory depression and reduced cardiac output; may precipitate acute circulatory failure in cardiovascular disease (especially constrictive pericarditis). Keep intubation, oxygen and resuscitation equipment available.نشرة دولية لنفس التركيبة · electronic medicines compendium (emc), UK
• Severe or refractory hypokalaemia during infusion and rebound hyperkalaemia after stopping have been reported (raised ICP use). May cause addiction.نشرة دولية لنفس التركيبة · electronic medicines compendium (emc), UK
• Special care in hypovolaemia, severe haemorrhage, burns, myasthenia gravis, adrenocortical insufficiency, cachexia, raised ICP, raised blood urea; reduce dose in shock, dehydration, severe anaemia, hyperkalaemia, toxaemia, thyrotoxicosis, myxoedema and diabetes. Out-patients should not drive or use machines for 24-36 hours.نشرة دولية لنفس التركيبة · electronic medicines compendium (emc), UK

• Use only when expected benefit outweighs potential risk; animal studies showed reproductive toxicity. Thiopental readily crosses the placenta.نشرة دولية لنفس التركيبة · electronic medicines compendium (emc), UK
• Appears in breast milk; suspend breastfeeding for at least 12 hours (or express milk before induction).نشرة دولية لنفس التركيبة · electronic medicines compendium (emc), UK