سعر Thrombexx 15mg/ml s.c. 3 amp. 2026

Recombinant hirudin (desirudin) 15 mg/1 ml powder and solvent for subcutaneous injection, 3 ampoules (Egypt).

• Haemorrhage, anaemia, allergic reactions, hypotension, deep thrombophlebitis, nausea, fever, injection-site cyst, haematoma, leg oedema.General active-ingredient information · Vidal Vademecum

• Hypersensitivity to hirudins; active bleeding and/or irreversible coagulation disorders; severe hepatic or renal impairment (CrCl <30 ml/min); pregnancy; severe uncontrolled hypertension; subacute bacterial endocarditis.General active-ingredient information · Vidal Vademecum

• Fatal anaphylactic reactions on re-exposure; caution in patients previously exposed to hirudin or analogues.General active-ingredient information · Vidal Vademecum
• High bleeding risk situations (recent major surgery, biopsy, haemorrhagic stroke, intracranial/intraocular bleeding, recent GI or pulmonary bleeding): monitor aPTT (maximum 2 times control); bleeding risk increased with anticoagulants, antiplatelets or NSAIDs.General active-ingredient information · Vidal Vademecum
• Caution in mild-moderate hepatic or renal impairment (CrCl 31-90 ml/min) with aPTT monitoring; no experience in children.General active-ingredient information · Vidal Vademecum

• Heparins and dextransDo not combine.Vidal Vademecum
• Anticoagulants, antiplatelet agents, NSAIDsIncreased bleeding risk.Vidal Vademecum

• Contraindicated in pregnancy; exclude pregnancy (pregnancy test) in women of childbearing potential; spina bifida (rabbits) and umbilical hernia (rats) seen in animal studies at therapeutic-range doses.General active-ingredient information · Vidal Vademecum
• Unknown whether excreted in breast milk; mothers should avoid breastfeeding or use an alternative drug.General active-ingredient information · Vidal Vademecum

• Recombinant hirudin (desirudin): Potent and selective thrombin inhibitor.