دواعي استعمال تيجيفاركو 50 مجم فيال

Tigecycline 50 mg powder for intravenous infusion (glycylcycline antibacterial), single vial, marketed in Egypt by Pharco.

• Complicated skin and skin structure infections caused by susceptible bacteriaالفئة: Patients 18 years and olderDailyMed (U.S. National Library of Medicine)
• Complicated intra-abdominal infections caused by susceptible bacteriaالفئة: Patients 18 years and olderDailyMed (U.S. National Library of Medicine)
• Community-acquired bacterial pneumonia caused by susceptible bacteriaالفئة: Patients 18 years and olderDailyMed (U.S. National Library of Medicine)

• Most common adverse reactions (incidence >5%): nausea, vomiting, diarrhoea, abdominal pain, headache and increased SGPT.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Known hypersensitivity to tigecycline or any excipient; reactions have included anaphylaxis.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Boxed warning: increased all-cause mortality versus comparators in a meta-analysis of Phase 3/4 trials (risk difference 0.6%); reserve for situations where alternative treatments are not suitable.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Pancreatitis, including fatalities, has been reported; consider stopping if suspected.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Use during tooth development (last half of pregnancy, infancy, childhood to age 8) may cause permanent tooth discoloration and enamel hypoplasia, and reversible inhibition of bone growth.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• WarfarinMonitor prothrombin time or another suitable anticoagulation test.DailyMed (U.S. National Library of Medicine)
• Calcineurin inhibitors (tacrolimus, ciclosporin)Monitor serum concentrations because of risk of toxicity.DailyMed (U.S. National Library of Medicine)

• Like other tetracycline-class drugs it may cause permanent discoloration of deciduous teeth and reversible inhibition of bone growth when given in the second and third trimesters; no data on major birth defects or miscarriage.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Avoid breastfeeding for longer than 3 weeks while taking tigecycline; alternatively pump and discard milk during treatment and for 9 days after the last dose.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Hypofibrinogenaemia has been reported; monitor coagulation parameters including fibrinogen at baseline and regularly during treatment.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)