دواعي استعمال تيماسبان 1000مجم 10 اقراص
معلومات من نشرات دوائية ومراجع موثقة، مع مصدر كل معلومة. السعر الحالي: 28.8ج.م.
دواعي الاستعمال
- Adjunct to diet to reduce elevated TC, LDL-C, Apo B and TG and to increase HDL-C in primary hyperlipidemia and mixed dyslipidemiaالفئة: AdultsDailyMed (U.S. National Library of Medicine)
- Adjunctive therapy in adults with severe hypertriglyceridemia at risk of pancreatitisالفئة: AdultsDailyMed (U.S. National Library of Medicine)
الآثار الجانبية
- Most common (>5% and greater than placebo): flushing, diarrhea, nausea, vomiting, increased cough and pruritus.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
موانع الاستعمال
- Active liver disease or unexplained persistent elevations in hepatic transaminases; active peptic ulcer disease; arterial bleeding; hypersensitivity to niacin or any component.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
تحذيرات واحتياطات
- Extended-release niacin must not be substituted for equivalent doses of immediate-release niacin; severe hepatic toxicity has occurred with such substitution. Risk of myopathy/rhabdomyolysis, especially with statins.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
التداخلات الدوائية
- StatinsCaution: increased risk of myopathy/rhabdomyolysis with niacin (>=1 g/day).DailyMed (U.S. National Library of Medicine)
- Bile acid sequestrantsSeparate by 4-6 hours (sequestrant taken before niacin) because of high niacin-binding capacity.DailyMed (U.S. National Library of Medicine)
- Antihypertensives / vasoactive drugsNiacin may potentiate ganglionic blockers and vasoactive drugs, causing postural hypotension.DailyMed (U.S. National Library of Medicine)
المصادر
- السعر: قوائم أسعار الأدوية المنشورة في مصر.
- DailyMed (U.S. National Library of Medicine)
- PubChem (NCBI)
- WHO Collaborating Centre for Drug Statistics Methodology (ATC/DDD Index)