دواعي استعمال تونس 5 مجم

Selegiline 5 mg tablets, 30 tablets (Alfacure Pharmaceuticals, Egypt); MAO-B inhibitor for Parkinson's disease.

• Adjunct in Parkinsonian patients on levodopa/carbidopa who show deterioration in their response to therapy.DailyMed (U.S. National Library of Medicine)

• Known hypersensitivity to selegiline.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)
• Use with meperidine (often extended to other opioids).نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)

• Rare hypertensive reactions with tyramine-containing foods have occurred even at the recommended dose; selectivity falls as dose increases.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)
• Avoid combination with tricyclic antidepressants and SSRIs (severe CNS toxicity/serotonin-type reactions); allow at least 14 days after stopping selegiline before starting a tricyclic antidepressant.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)

• MeperidineStupor, muscular rigidity, severe agitation and elevated temperature reported; contraindicated.DailyMed (U.S. National Library of Medicine)
• Sympathomimetics (e.g. ephedrine)A hypertensive crisis was reported with selegiline at recommended dose plus ephedrine.DailyMed (U.S. National Library of Medicine)

• No teratogenic effects in rat and rabbit embryo-fetal studies; label carries historical Pregnancy Category C.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)
• Unknown whether selegiline is excreted in human milk; consider discontinuing non-essential drugs in nursing women.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)