دواعي استعمال توجيو سولوستار 300وحدة/مل 1.5مل 3 اقلام
معلومات من نشرات دوائية ومراجع موثقة، مع مصدر كل معلومة. السعر الحالي: 1,416ج.م.
دواعي الاستعمال
- To improve glycemic control in adults and pediatric patients 6 years and older with diabetes mellitusالفئة: Adults and children >=6 yearsDailyMed (U.S. National Library of Medicine)
الآثار الجانبية
- Common (>=5%): hypoglycaemia, allergic reactions, injection site reactions, lipodystrophy, pruritus, rash, oedema and weight gain.نشرة دولية لنفس المنتج · DailyMed (U.S. National Library of Medicine)
موانع الاستعمال
- During episodes of hypoglycaemia.نشرة دولية لنفس المنتج · DailyMed (U.S. National Library of Medicine)
- Hypersensitivity to insulin glargine or any excipient.نشرة دولية لنفس المنتج · DailyMed (U.S. National Library of Medicine)
تحذيرات واحتياطات
- Changes in insulin regimen (strength, manufacturer, type, site or method) may cause hyper- or hypoglycaemia; make changes under close medical supervision.نشرة دولية لنفس المنتج · DailyMed (U.S. National Library of Medicine)
- Hypoglycaemia may be life-threatening; medication errors from insulin mix-ups can occur, so check insulin labels before each injection.نشرة دولية لنفس المنتج · DailyMed (U.S. National Library of Medicine)
- Severe generalized allergy including anaphylaxis can occur.نشرة دولية لنفس المنتج · DailyMed (U.S. National Library of Medicine)
- Hypokalaemia may be life-threatening; monitor potassium in patients at risk.نشرة دولية لنفس المنتج · DailyMed (U.S. National Library of Medicine)
- Fluid retention and heart failure may occur with concomitant thiazolidinediones.نشرة دولية لنفس المنتج · DailyMed (U.S. National Library of Medicine)
التداخلات الدوائية
- Antidiabetic agents, ACE inhibitors, ARBs, fibrates, fluoxetine, MAOIs, salicylates, sulfonamides, GLP-1 agonists, DPP-4 and SGLT-2 inhibitorsMay increase hypoglycaemia risk; dose reduction and more frequent glucose monitoring may be required.DailyMed (U.S. National Library of Medicine)
- Atypical antipsychotics, corticosteroids, diuretics, estrogens/progestogens, isoniazid, niacin, somatropin, sympathomimetics, thyroid hormonesMay decrease the glucose-lowering effect; dose increase and more frequent monitoring may be required.DailyMed (U.S. National Library of Medicine)
- Alcohol, beta-blockers, clonidine, lithium, pentamidineMay increase or decrease the glucose-lowering effect; beta-blockers and clonidine may blunt signs of hypoglycaemia.DailyMed (U.S. National Library of Medicine)
الحمل والرضاعة
- Published studies have not reported a clear association between insulin glargine and adverse developmental outcomes; poorly controlled diabetes carries maternal and fetal risks.نشرة دولية لنفس المنتج · DailyMed (U.S. National Library of Medicine)
- No or limited data on insulin glargine in human milk; endogenous insulin is present in milk. Weigh benefits of breastfeeding against maternal need.نشرة دولية لنفس المنتج · DailyMed (U.S. National Library of Medicine)
المتابعة أثناء العلاج
- Monitor blood glucose, especially when initiating or switching; maximum effect may take five days.نشرة دولية لنفس المنتج · DailyMed (U.S. National Library of Medicine)
كيف يعمل الدواء
- إنسولين جلارجين: Lowers blood glucose by stimulating peripheral glucose uptake (skeletal muscle, fat) and inhibiting hepatic glucose production; inhibits lipolysis and proteolysis (US label).
المصادر
- السعر: قوائم أسعار الأدوية المنشورة في مصر.
- DailyMed (U.S. National Library of Medicine)