سعر تراموندين Tramundin‏ 100مجم اس ار 10 اقراص 2026

Tramundin (tramadol hydrochloride) 100 mg sustained-release tablets, pack of 10 (Mundipharma, supplied in Egypt by MUP).

• Most common adverse reactions are nausea and dizziness (more than 10% of patients); others include cardiovascular regulation effects (palpitation, tachycardia), rarely bradycardia.International label, equivalent formulation · electronic medicines compendium (emc)

• Hypersensitivity to tramadol or to any of the excipients.International label, equivalent formulation · electronic medicines compendium (emc)
• Acute intoxication with alcohol, hypnotics, analgesics, opioids or other psychotropic medicines.International label, equivalent formulation · electronic medicines compendium (emc)
• Patients receiving MAO inhibitors or who have taken them within the last 14 days.International label, equivalent formulation · electronic medicines compendium (emc)

• Concomitant use with sedating medicines such as benzodiazepines or other CNS depressants (including alcohol) increases the risk of sedation, respiratory depression, coma and death; reserve for patients without alternatives.International label, equivalent formulation · electronic medicines compendium (emc)
• Serotonin syndrome, potentially life-threatening, has been reported with tramadol alone or combined with other serotonergic agents.International label, equivalent formulation · electronic medicines compendium (emc)
• Tramadol is metabolised by CYP2D6: poor metabolisers may get inadequate analgesia, while ultra-rapid metabolisers risk opioid toxicity even at usual doses.International label, equivalent formulation · electronic medicines compendium (emc)

• MAO inhibitorsContraindicated: life-threatening CNS, respiratory and cardiovascular interactions cannot be ruled out with MAO inhibitors taken within 14 days.electronic medicines compendium (emc)
• Benzodiazepines and other CNS depressants (including alcohol)Increased risk of sedation, respiratory depression, coma and death.electronic medicines compendium (emc)

• Inadequate evidence on safety in human pregnancy; tramadol crosses the placenta and should not be used in pregnant women. Regular use may cause neonatal opioid withdrawal syndrome.International label, equivalent formulation · electronic medicines compendium (emc)
• Administration to nursing women is not recommended as tramadol may be secreted in breast milk and may cause respiratory depression in the infant.International label, equivalent formulation · electronic medicines compendium (emc)

• Tramadol hydrochloride: Centrally acting analgesic with mu-opioid activity plus inhibition of neuronal noradrenaline and serotonin reuptake; metabolised by CYP2D6 to an active metabolite.