دواعي استعمال ترينتوكسيمال 20مجم/مل 5 امبول 100 مجم per ampoule

Trentoximal ampoules containing pentoxifylline 100 mg (20 mg/ml per Arabic name), an anti-ischaemic haemorheologic agent, marketed in Egypt (Alexandria > Egypharma-Egypt).

• Peripheral vascular diseaseالفئة: AdultsHealth Products Regulatory Authority (HPRA), Ireland
• Cerebrovascular insufficiency (increase in cerebral blood flow not necessarily accompanied by clinical improvement)الفئة: AdultsHealth Products Regulatory Authority (HPRA), Ireland

• Hypersensitivity to pentoxifylline or other methylxanthines; cerebral haemorrhage; extensive retinal haemorrhage; acute myocardial infarction.نشرة دولية لتركيبة مكافئة · Health Products Regulatory Authority (HPRA), Ireland

• Careful monitoring in severe cardiac arrhythmias, myocardial infarction, diabetes mellitus and increased bleeding tendency; caution in hypotension or severe coronary artery disease (transient hypotension may reduce coronary perfusion).نشرة دولية لتركيبة مكافئة · Health Products Regulatory Authority (HPRA), Ireland

• Insulin and oral antidiabetic agentsMay enhance hypoglycaemic effect (increased insulin release); insulin dose reduction occasionally needed.Health Products Regulatory Authority (HPRA), Ireland
• Antihypertensive agentsMay potentiate antihypertensive effect; dose reduction of the antihypertensive may be needed.Health Products Regulatory Authority (HPRA), Ireland
• TheophyllineMay increase theophylline levels in some patients.Health Products Regulatory Authority (HPRA), Ireland
• KetorolacDo not co-administer: increased risk of bleeding and/or prolonged prothrombin time.Health Products Regulatory Authority (HPRA), Ireland

• Use in pregnancy is contraindicated (Irish SmPC).نشرة دولية لتركيبة مكافئة · Health Products Regulatory Authority (HPRA), Ireland
• Should not be used in women breastfeeding infants (Irish SmPC).نشرة دولية لتركيبة مكافئة · Health Products Regulatory Authority (HPRA), Ireland

• Monitor patients with cardiac arrhythmias, recent MI, diabetes or bleeding tendency; blood glucose in diabetics on insulin/oral agents.نشرة دولية لتركيبة مكافئة · Health Products Regulatory Authority (HPRA), Ireland