دواعي استعمال تريوجيكت 0.1 مجم/مل 5 سرنجة

Treoject pre-filled syringes containing octreotide 0.1 mg/ml (100 mcg/ml), a somatostatin analogue, listed in Egypt by Aboukir Trading.

• Acromegaly: to reduce blood GH and IGF-1 when response to or candidacy for surgery, radiation or bromocriptine is inadequateالفئة: AdultsDailyMed (U.S. National Library of Medicine)
• Severe diarrhea and flushing episodes associated with metastatic carcinoid tumorsالفئة: AdultsDailyMed (U.S. National Library of Medicine)
• Profuse watery diarrhea associated with VIP-secreting tumors (VIPomas)الفئة: AdultsDailyMed (U.S. National Library of Medicine)

• Gallbladder abnormalities (biliary abnormalities in a large proportion of acromegaly trial patients), sinus bradycardia, diarrhea, loose stools, nausea, abdominal discomfort, flatulence, hyperglycemia, hypothyroidism, injection-site pain.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)

• Sensitivity to octreotide or any of its components.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)

• Cholelithiasis and gallbladder sludge; complications of cholelithiasis may require discontinuation.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)
• Hypoglycemia or hyperglycemia due to altered counter-regulatory hormones; monitor glucose, adjust antidiabetic therapy.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)
• Hypothyroidism: monitor thyroid function with chronic therapy.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)
• Cardiac conduction abnormalities, bradycardia and arrhythmias; dose adjustment of beta-blockers/calcium channel blockers may be needed.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)
• Steatorrhea/fat malabsorption and decreased vitamin B12 levels with chronic use.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)

• CyclosporineOctreotide may decrease cyclosporine blood levels (transplant rejection reported).DailyMed (U.S. National Library of Medicine)
• Insulin and oral hypoglycemic agentsDose adjustment may be required because of altered glucose regulation.DailyMed (U.S. National Library of Medicine)
• Beta-blockers, calcium channel blockers, drugs affecting fluid/electrolytesDose adjustment may be necessary (additive bradycardia/conduction effects).DailyMed (U.S. National Library of Medicine)
• BromocriptineOctreotide increases bromocriptine availability.DailyMed (U.S. National Library of Medicine)
• Lutetium Lu 177 dotatateSomatostatin analogues competitively bind somatostatin receptors; discontinue short-acting octreotide at least 24 hours before each Lu-177 dotatate dose.DailyMed (U.S. National Library of Medicine)

• Limited data in pregnant women are insufficient to inform a drug-associated risk; may increase chance of pregnancy in women with acromegaly (counsel on contraception).نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)
• No data on presence in human milk or effects on the breastfed infant (US label).نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)

• Gallbladder ultrasound periodically, thyroid function, blood glucose, vitamin B12 with chronic use, GH/IGF-1 in acromegaly, heart rate/ECG where indicated.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)