دواعي استعمال تريكوجيل 0.75% جل مهبلي 30 جم

جل مهبلي ميترونيدازول 0.75%، أنبوب 30 جم؛ لعلاج التهاب المهبل البكتيري موضعيًا.

• علاج التهاب المهبل البكتيريالفئة: Non-pregnant and pregnant women (adults)DailyMed (U.S. National Library of Medicine)

• Most common adverse reactions in clinical trials: vaginal discharge (12%), symptomatic Candida cervicitis/vaginitis (10%), vulvovaginal irritation (9%), gastrointestinal discomfort (7%), headache (5%), nausea (4%).نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• فرط الحساسية للميترونيدازول أو البارابين أو مشتقات النيتروإيميدازول.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Patients who have taken disulfiram within the last 2 weeks (psychotic reactions reported with oral metronidazole and disulfiram).نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Convulsive seizures and peripheral neuropathy have been reported with metronidazole; stop treatment if abnormal neurologic signs appear; use with caution in patients with CNS diseases.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Use with caution in severe hepatic disease (reduced metronidazole clearance).نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Symptomatic Candida vaginitis may emerge during or after therapy (reported in about 6-10% of patients).نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• A disulfiram-like reaction to alcohol is possible; avoid contact with the eyes; vaginal intercourse is not recommended during treatment.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Warfarin and other coumarin anticoagulantsOral metronidazole potentiates the anticoagulant effect of warfarin and coumarins (prolonged prothrombin time); the label advises considering this with the vaginal gel.DailyMed (U.S. National Library of Medicine)
• LithiumOral metronidazole has been reported to raise serum lithium; the label cites this interaction.DailyMed (U.S. National Library of Medicine)
• CimetidineCimetidine may prolong the half-life and decrease the clearance of metronidazole.DailyMed (U.S. National Library of Medicine)
• DisulfiramPsychotic reactions have been reported in alcoholic patients using oral metronidazole with disulfiram; do not use within 2 weeks of disulfiram.DailyMed (U.S. National Library of Medicine)

• Historical US pregnancy category B; there are no adequate and well-controlled studies in pregnant women, and the gel should be used in pregnancy only if clearly needed.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Metronidazole is secreted in human milk after oral use; because of tumorigenicity in animal studies, a decision should be made whether to discontinue nursing or the drug.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Metronidazole may interfere with certain serum chemistry assays (AST, ALT, LDH, triglycerides, glucose hexokinase), giving falsely low or zero values.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• ميترونيدازول: مضاد ميكروبات من فئة النيتروإيميدازول