دواعي استعمال تريتاس كومب مركب 5/25 مجم 14 قرص

Ramipril 5 mg + hydrochlorothiazide 25 mg tablets, pack of 14 (Sanofi, Egyptian market).

• Essential hypertension in patients whose blood pressure is not adequately lowered by ramipril alone or hydrochlorothiazide aloneالفئة: AdultsIsrael Ministry of Health drug registry

• Hypersensitivity to ramipril or other ACE inhibitors, hydrochlorothiazide, other thiazides, sulfonamides or excipients; history of angioedema; concomitant sacubitril/valsartan; extracorporeal treatments with negatively charged surfaces.نشرة دولية لنفس التركيبة · Israel Ministry of Health drug registry
• Significant bilateral renal artery stenosis or stenosis in a single kidney; CrCl <30 mL/min; clinically relevant electrolyte disturbances; severe hepatic impairment; hepatic encephalopathy.نشرة دولية لنفس التركيبة · Israel Ministry of Health drug registry
• Second and third trimesters of pregnancy; lactation; aliskiren with diabetes mellitus or GFR <60 mL/min/1.73 m2.نشرة دولية لنفس التركيبة · Israel Ministry of Health drug registry

• Risk of acute hypotension and renal deterioration with a strongly activated RAAS; correct volume/salt depletion before starting.نشرة دولية لنفس التركيبة · Israel Ministry of Health drug registry
• Electrolyte imbalance (hypokalaemia, hyponatraemia, hypomagnesaemia, hypercalcaemia) and hyperkalaemia; monitor electrolytes.نشرة دولية لنفس التركيبة · Israel Ministry of Health drug registry
• Angioedema (including intestinal), neutropenia/agranulocytosis and cough may occur.نشرة دولية لنفس التركيبة · Israel Ministry of Health drug registry
• Hydrochlorothiazide: choroidal effusion, acute myopia and angle-closure glaucoma; very rare acute respiratory distress syndrome; increased non-melanoma skin cancer risk with cumulative exposure; metabolic effects.نشرة دولية لنفس التركيبة · Israel Ministry of Health drug registry

• Lithium saltsReduced lithium excretion with increased toxicity risk; combination not recommended.Israel Ministry of Health drug registry

• Contraindicated during breast-feeding.نشرة دولية لنفس التركيبة · Israel Ministry of Health drug registry